p-Cyanohippursaeureethylester

Base Information

• Chemical Name: p-Cyanohippursaeureethylester
• CAS No.: 207864-23-1
• Molecular Formula: C₁₂H₁₂N₂O₃
• Molecular Weight: 232.239
• Mol file: 207864-23-1.mol

Synonyms:p-Cyanohippursaeureethylester

Chemical Property of p-Cyanohippursaeureethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of p-Cyanohippursaeureethylester

There total 4 articles about p-Cyanohippursaeureethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H7ClN2O4 (1644630-63-6) + GlyOEt*HCl (459-73-4) → p-Cyanohippursaeureethylester (207864-23-1)

Guidance literature:

In water; dimethyl sulfoxide; acetonitrile; at 25 ℃;

DOI:10.5012/bkcs.2014.35.8.2271

Reference yield:

4-cyanobenzoyl chlorIde (6068-72-0) → p-Cyanohippursaeureethylester (207864-23-1)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / diethyl ether

2: acetonitrile; dimethyl sulfoxide; water / 25 °C

With triethylamine; In diethyl ether; water; dimethyl sulfoxide; acetonitrile;

DOI:10.5012/bkcs.2014.35.8.2271

Reference yield:

4-cyanobenzoic Acid (619-65-8,333406-09-0) + glycine ethyl ester hydrochloride (623-33-6) → p-Cyanohippursaeureethylester (207864-23-1)

Guidance literature:

With 1,1'-carbonyldiimidazole; Yield given. Multistep reaction; 1) DMF, 0 deg C -> room temperature, 20 min, 2) DMF, room temperature, 30 min;

DOI:10.1080/00397919808006857

upstream raw materials:

4-cyanobenzoic Acid

glycine ethyl ester hydrochloride

4-cyanobenzoyl chlorIde

C₁₄H₇ClN₂O₄