1-(para-toluenesulfonyl)tetradecyne

Base Information

• Chemical Name: 1-(para-toluenesulfonyl)tetradecyne
• CAS No.: 1432726-55-0
• Molecular Formula: C₂₁H₃₂O₂S
• Molecular Weight: 348.55
• Mol file: 1432726-55-0.mol

Synonyms:1-(para-toluenesulfonyl)tetradecyne

Chemical Property of 1-(para-toluenesulfonyl)tetradecyne

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(para-toluenesulfonyl)tetradecyne

There total 1 articles about 1-(para-toluenesulfonyl)tetradecyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1-tetradecyne (765-10-6) + p-tolyl benzeneselenosulfonate (68819-94-3) → 1-(para-toluenesulfonyl)tetradecyne (1432726-55-0)

Guidance literature:

1-tetradecyne; p-tolyl benzeneselenosulfonate; In chloroform; for 2.5h; Irradiation;

With 3-chloro-benzenecarboperoxoic acid; In chloroform; for 3.41667h; Reflux;

DOI:10.1002/chem.201202307

Reference yield: 88.0%

1-(para-toluenesulfonyl)tetradecyne (1432726-55-0) + 4-formylamino-3-iodo-benzoic acid methyl ester (514805-23-3) → (E)-methyl 3-iodo-4-[N-(1-p-toluenesulfonyltetradec-2-en-2-yl)formamido]-benzoate (1432726-65-2)

Guidance literature:

With potassium carbonate; In water; N,N-dimethyl-formamide; at 20 ℃; for 16h;

DOI:10.1002/chem.201202307

Reference yield: 84.0%

N-(4-cyano-2-iodophenyl)formamide (924627-26-9) + 1-(para-toluenesulfonyl)tetradecyne (1432726-55-0) → (E)-N-(4-cyano-2-iodophenyl)-N-[(1-p-toluenesulfonyl)tetradec-2-en-2-yl]formamide (1432726-64-1)

Guidance literature:

With potassium carbonate; In water; N,N-dimethyl-formamide; at 20 ℃; for 16h;

DOI:10.1002/chem.201202307

upstream raw materials:

1-tetradecyne

p-tolyl benzeneselenosulfonate

Downstream raw materials:

2-n-dodecyl-5-methyl-3-(p-toluenesulfonyl)-1H-indole

2-n-dodecyl-3-(p-toluenesulfonyl)-1H-indole

methyl 2-n-dodecyl-3-(p-toluenesulfonyl)-1H-indole-5-carboxylate

(E)-N-(2-iodophenyl)-N-[(1-p-toluenesulfonyl)tetradec-2-en-2-yl]formamide