1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

Base Information

• Chemical Name: 1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol
• CAS No.: 1071592-05-6
• Molecular Formula: C₅₁H₈₀N₂O₇Si
• Molecular Weight: 861.291
• Mol file: 1071592-05-6.mol

Synonyms:1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

Chemical Property of 1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

There total 1 articles about 1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol (946827-19-6) + 1-hexadecylcarboxylic acid (57-10-3) → 1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol (1071592-05-6)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1016/j.bmc.2008.07.010

Reference yield: 80.0%

1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol (1071592-05-6) → 1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]glycerol (1071592-12-5)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/j.bmc.2008.07.010

upstream raw materials:

1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

1-hexadecylcarboxylic acid

Downstream raw materials:

1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]glycerol