1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

Base Information

Chemical Name:1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol
CAS No.:946827-19-6
Molecular Formula:C₃₅H₅₀N₂O₆Si
Molecular Weight:622.877
Hs Code.:

Synonyms:1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

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Chemical Property of 1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

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Technology Process of 1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

There total 1 articles about 1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 110-60-1
1,4-diaminobutane

: 530-62-1
1,1'-carbonyldiimidazole

: 1-O-(4,4'-dimethoxytrityl)-3-O-tert-butyldimethylsilylglycerol

: 946827-19-6
1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

Guidance literature:: 1,1'-carbonyldiimidazole; 1-O-(4,4'-dimethoxytrityl)-3-O-tert-butyldimethylsilylglycerol; With pyridine; at 20 ℃; for 1h;

1,4-diaminobutane; at 0 - 20 ℃; for 3h;
DOI:10.1016/j.bmc.2008.07.010

Reference yield: 86.0%

: 112-80-1,2027-47-6
cis-Octadecenoic acid

: 946827-19-6
1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

: 946827-23-2
1-O-(4,4'-dimethoxytrityl)-2-O-[N-oleoyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1016/j.bmc.2008.07.010

Reference yield: 69.0%

: 946827-19-6
1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

: 57-10-3
1-hexadecylcarboxylic acid

: 1071592-05-6
1-O-(4,4'-dimethoxytrityl)-2-O-[N-palmitoyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1016/j.bmc.2008.07.010