Phenol, 2,2'-(1,2-ethanediylidenedinitrilo)bis-

Base Information

• Chemical Name: Phenol, 2,2'-(1,2-ethanediylidenedinitrilo)bis-
• CAS No.: 1149-16-2
• Molecular Formula: C14H12N2O2
• Molecular Weight: 240.261
• Hs Code.: 29252000
• European Community (EC) Number: 214-560-0
• NSC Number: 68050
• UNII: E2AW5XX09U
• DSSTox Substance ID: DTXSID7061568
• Nikkaji Number: J7.285K
• Wikidata: Q27276775
• Mol file: 1149-16-2.mol

Synonyms:GBHA;glyoxal bis(2-hydroxyanil);glyoxal-bis(2-hydroxyanil)

Chemical Property of Phenol, 2,2'-(1,2-ethanediylidenedinitrilo)bis-

Chemical Property:

• Appearance/Colour: off-white to tan powder
• Vapor Pressure: 1.92E-07mmHg at 25°C
• Melting Point: 203-211 °C(lit.)
• Refractive Index: 1.596
• Boiling Point: 448.413 °C at 760 mmHg
• PKA: 9.46±0.35(Predicted)
• Flash Point: 293.841 °C
• PSA: 65.18000
• Density: 1.172 g/cm³
• LogP: 3.20260
• Storage Temp.: Store at +15°C to +25°C.
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slig
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 240.089877630
• Heavy Atom Count: 18
• Complexity: 274

Purity/Quality:

99% ^*data from raw suppliers

Glyoxal Bis(2-hydroxyanil) >98.0%(N) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Aromatics (Nitrogen)
• Canonical SMILES: C1=CC=C(C(=C1)N=CC=NC2=CC=CC=C2O)O

Technology Process of Phenol, 2,2'-(1,2-ethanediylidenedinitrilo)bis-

There total 3 articles about Phenol, 2,2'-(1,2-ethanediylidenedinitrilo)bis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

Glyoxal (131543-46-9,107-22-2) + 2-amino-phenol (95-55-6) → glyoxal-bis-(2-hydroxyanil) (1149-16-2)

Guidance literature:

In ethanol; water; Inert atmosphere;

DOI:10.1021/ic5006314

Reference yield:

Glyoxal (131543-46-9,107-22-2) + 2-amino-phenol (95-55-6) → 2,2′-(((1E,2E)-ethane-1,2-diylidene)bis(azaneylylidene))diphenol (1149-16-2)

Guidance literature:

With acetic acid; In ethanol; at 75 ℃; for 5h;

DOI:10.1016/j.jphotochem.2021.113346

Reference yield:

→ 2,2′-(((1E,2E)-ethane-1,2-diylidene)bis(azaneylylidene))diphenol (1149-16-2)

Guidance literature:

Glyoxal, o-Aminophenol;

DOI:10.1002/zaac.19723870114

upstream raw materials:

Glyoxal

2-amino-phenol

Refernces

• 1、 Bianca et al.. "". . p. 126,129, 132. Retrieved 1972.
• 2、 Miki, Yuya,Sajiki, Hironao,Sawama, Yoshinari. "N-Heterocyclic Carbene Catalyzed Deuteration of Aldehydes in D 2 O". supporting information. p. 699 - 702. Retrieved 2020/04/07.