(S)-2--3-(4-hydroxyphenyl)propanoate d'ethyle

Base Information

• Chemical Name: (S)-2--3-(4-hydroxyphenyl)propanoate d'ethyle
• CAS No.: 168846-66-0
• Molecular Formula: C₁₇H₂₀N₂O₃
• Molecular Weight: 300.357
• Mol file: 168846-66-0.mol

Synonyms:(S)-2--3-(4-hydroxyphenyl)propanoate d'ethyle

Chemical Property of (S)-2--3-(4-hydroxyphenyl)propanoate d'ethyle

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (S)-2--3-(4-hydroxyphenyl)propanoate d'ethyle

There total 1 articles about (S)-2--3-(4-hydroxyphenyl)propanoate d'ethyle which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

L-tyrosine ethyl ester monohydrochloride (4089-07-0) + 2-oxocyclopentanecarbonitrile (2941-29-9,138260-51-2) → (S)-2--3-(4-hydroxyphenyl)propanoate d'ethyle (168846-66-0)

Guidance literature:

With sodium hydroxide; In water; for 48h; Ambient temperature;

DOI:10.1002/hlca.19950780111

Reference yield: 96.3%

2-iodo-propane (75-30-9) + (S)-2--3-(4-hydroxyphenyl)propanoate d'ethyle (168846-66-0) → (S)-2--3-<4-(isopropoxy)phenyl>propanoate d'ethyle

Guidance literature:

With sodium ethanolate; In N,N-dimethyl-formamide; for 48h; Ambient temperature; 1.) room temp., 15 min;

DOI:10.1002/hlca.19950780111

Reference yield: 90.5%

dimethyl sulfate (77-78-1) + (S)-2--3-(4-hydroxyphenyl)propanoate d'ethyle (168846-66-0) → (2S)-2--3-(4-methoxyphenyl)propanoate d'ethyle

Guidance literature:

With sodium ethanolate; In N,N-dimethyl-formamide; for 6h; Ambient temperature; 1.) room temp., 15 min;

DOI:10.1002/hlca.19950780111

upstream raw materials:

L-tyrosine ethyl ester monohydrochloride

2-oxocyclopentanecarbonitrile

Refernces