2-{[3-(Acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinic acid 1-benzyl ester 4-(4-nitro-phenyl) ester

Base Information

Chemical Name:2-{[3-(Acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinic acid 1-benzyl ester 4-(4-nitro-phenyl) ester
CAS No.:83948-74-7
Molecular Formula:C₃₁H₃₃N₃O₁₀
Molecular Weight:607.617
Hs Code.:

Synonyms:2-{[3-(Acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinic acid 1-benzyl ester 4-(4-nitro-phenyl) ester

Suppliers and Price of 2-{[3-(Acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinic acid 1-benzyl ester 4-(4-nitro-phenyl) ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-{[3-(Acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinic acid 1-benzyl ester 4-(4-nitro-phenyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-{[3-(Acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinic acid 1-benzyl ester 4-(4-nitro-phenyl) ester

There total 9 articles about 2-{[3-(Acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinic acid 1-benzyl ester 4-(4-nitro-phenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2687-43-6
O-benzylhydoxylamine hydrochloride

: 83948-74-7
2-{[3-(Acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinic acid 1-benzyl ester 4-(4-nitro-phenyl) ester

Guidance literature:: Multi-step reaction with 5 steps

1: 60 percent / pyridine / acetonitrile / 1.) 0 deg C, 2.) 24 h, room temperature

2: 78 percent / PPh₃, DEAD / tetrahydrofuran / 1.5 h / Ambient temperature

3: 65 percent / H₂ / 5percent Pd/C / ethyl acetate / 3 h / 0 °C / 760 Torr

4: 97 percent / HCl gas / diethyl ether / 0 °C

5: Et₃N / acetonitrile / 3.5 h / Ambient temperature

With pyridine; hydrogenchloride; hydrogen; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; diethyl ether; ethyl acetate; acetonitrile;
DOI:10.1021/jo00149a005

Reference yield:

: 15255-86-4
N-benzyloxycarbonyl-O-benzylhydroxylamine

: 83948-74-7
2-{[3-(Acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinic acid 1-benzyl ester 4-(4-nitro-phenyl) ester

Guidance literature:: Multi-step reaction with 4 steps

1: 78 percent / PPh₃, DEAD / tetrahydrofuran / 1.5 h / Ambient temperature

2: 65 percent / H₂ / 5percent Pd/C / ethyl acetate / 3 h / 0 °C / 760 Torr

3: 97 percent / HCl gas / diethyl ether / 0 °C

4: Et₃N / acetonitrile / 3.5 h / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; diethyl ether; ethyl acetate; acetonitrile;
DOI:10.1021/jo00149a005

Reference yield:

: 83948-52-1
O-Benzyl-N-(p-nitrobenzyloxycarbonyl)hydroxylamine

: 83948-74-7
2-{[3-(Acetyl-benzyloxy-amino)-propylcarbamoyl]-methyl}-2-hydroxy-succinic acid 1-benzyl ester 4-(4-nitro-phenyl) ester

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / PPh₃, DEAD / tetrahydrofuran / 1.5 h / Ambient temperature

2: 55 percent / H₂ / 5percent Pd/C / ethyl acetate / 3 h / 0 °C / 760 Torr

3: 97 percent / HCl gas / diethyl ether / 0 °C

4: Et₃N / acetonitrile / 3.5 h / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; diethyl ether; ethyl acetate; acetonitrile;
DOI:10.1021/jo00149a005