1-Ethylpiperazine-2,3-dione

Base Information

Chemical Name:1-Ethylpiperazine-2,3-dione
CAS No.:59702-31-7
Molecular Formula:C6H10N2O2
Molecular Weight:142.158
Hs Code.:29339900
European Community (EC) Number:261-866-5
UNII:GG5LCG550O
DSSTox Substance ID:DTXSID80208421
Nikkaji Number:J27.889K
Wikidata:Q72474639
Mol file:59702-31-7.mol

Synonyms:1-ethyl-2,3-dioxopiperazine

Suppliers and Price of 1-Ethylpiperazine-2,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Ethyl-2,3-dioxopiperazine
50g
$ 155.00

TRC
1-Ethyl-2,3-dioxopiperazine
100mg
$ 50.00

TCI Chemical
1-Ethyl-2,3-dioxopiperazine >98.0%(GC)
250g
$ 398.00

TCI Chemical
1-Ethyl-2,3-dioxopiperazine >98.0%(GC)
25g
$ 67.00

Sigma-Aldrich
1-ethyl-2,3-piperazinedione AldrichCPR
500mg
$ 144.00

Sigma-Aldrich
Piperacillin Related Compound E United States Pharmacopeia (USP) Reference Standard
25mg
$ 1160.00

Frontier Specialty Chemicals
1-Ethyl-2,3-dioxopiperazine 98%
25g
$ 81.00

Crysdot
1-Ethylpiperazine-2,3-dione 97%
100g
$ 134.00

Chem-Impex
1-Ethyl-2,3-dioxopiperazine,≥98%(GC) ≥98%(GC)
25G
$ 64.71

American Custom Chemicals Corporation
N-ETHYL-2,3-DIOXOPIPERAZINE 95.00%
5G
$ 1005.43

Total 117 raw suppliers

Chemical Property of 1-Ethylpiperazine-2,3-dione

Chemical Property:

Appearance/Colour:white to pale yellow crystalline powder
Melting Point:106-110 °C(lit.)
Refractive Index:1.475
Boiling Point:346oC
PKA:12.57±0.20(Predicted)
PSA：49.41000
Density:1.145 g/cm³
LogP:-0.76860
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:2000 g/L
Water Solubility.:2000 g/L
XLogP3:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:142.074227566
Heavy Atom Count:10
Complexity:167

Purity/Quality:

99% ^*data from raw suppliers

1-Ethyl-2,3-dioxopiperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCNC(=O)C1=O
Uses 1-Ethyl-2,3-dioxopiperazine is an intermediate used in the new process for the synthesis of Piperacillin sodium. 1-Ethyl-2,3-dioxopiperazine (Piperacillin EP Impurity E; Piperacillin USP Related Compound E) is an intermediate used in the new process for the synthesis of Piperacillin sodium.

Technology Process of 1-Ethylpiperazine-2,3-dione

There total 3 articles about 1-Ethylpiperazine-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.21%