Technology Process of 3-(2-carboxymethylbenzylthio)phenylacetonitrile
There total 8 articles about 3-(2-carboxymethylbenzylthio)phenylacetonitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: lithium aluminum hydride / tetrahydrofuran / 1 h
2: dimethylformamide; H2O / 0.33 h / Ambient temperature
3: 93.2 percent / dry hydrogen bromide / tetrahydrothiophene 1,1-dioxide / 2.75 h / 15 °C
4: acetone; H2O / 1 h / Heating
With
lithium aluminium tetrahydride; hydrogen bromide;
In
tetrahydrofuran; sulfolane; water; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 85.6 percent / chlorosulfonic acid / 2 h / 120 - 125 °C
2: lithium aluminum hydride / tetrahydrofuran / 1 h
3: dimethylformamide; H2O / 0.33 h / Ambient temperature
4: 93.2 percent / dry hydrogen bromide / tetrahydrothiophene 1,1-dioxide / 2.75 h / 15 °C
5: acetone; H2O / 1 h / Heating
With
chlorosulfonic acid; lithium aluminium tetrahydride; hydrogen bromide;
In
tetrahydrofuran; sulfolane; water; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dimethylformamide; H2O / 0.33 h / Ambient temperature
2: 93.2 percent / dry hydrogen bromide / tetrahydrothiophene 1,1-dioxide / 2.75 h / 15 °C
3: acetone; H2O / 1 h / Heating
With
hydrogen bromide;
In
sulfolane; water; N,N-dimethyl-formamide; acetone;
