Levofloxacin Q-Acid

Base Information Edit

Chemical Name:Levofloxacin Q-Acid
CAS No.:100986-89-8
Molecular Formula:C13H9F2NO4
Molecular Weight:281.216
Hs Code.:29349990
European Community (EC) Number:923-011-0,622-908-1
UNII:08GT8FY84E
DSSTox Substance ID:DTXSID60143604
Nikkaji Number:J795.481F
Mol file:100986-89-8.mol

Synonyms:100986-89-8;Levofloxacin Q-Acid;Levofloxacin carboxylic acid;(S)-9,10-Difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;Levofloxacin q-acid, (-)-;UNII-08GT8FY84E;08GT8FY84E;(2S)-6,7-difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid;(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine-6-carboxylic acid;7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-;Ofloxacin Impurity A;(S)-9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid;(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid;7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-;Levofloxacin impurity F;(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid;SCHEMBL2333806;DTXSID60143604;CHEBI:167723;MFCD04039905;AKOS016002127;AC-7592;FS-4544;(3S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid;CS-0136444;L0238;N17092;EN300-1655914;A897275;Q27236408;LEVOFLOXACIN HEMIHYDRATE IMPURITY F [EP IMPURITY];Z2681131293;8,9-difluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-azaphenalene-5-carboxylic acid;(-) -9,10-difluoro-3(S)-methyl-7-oxo-2,3-dihydro-7H -pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid;(-) -9,10-difluoro-3(S)-methyl-7-oxo-2,3-dihydro-7H-pyrido [1,2,3-de]-1,4-benzoxazine-6-carboxylic acid;(-)-9,10-difluoro-3(S)-methyl-7-oxo-2,3-dihydro-7H-pyrido [1,2,3-de]-1,4-benzoxazine-6-carboxylic acid;(-)-9,10-difluoro-3(S)-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid;(2S)-6,7-difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.0,5,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid;(3S)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid;(3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;(S)-(-) 9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4] benzoxazine-6-carboxylic acid;(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid 97%;(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 97%;(S)-(-)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido [1,2,3-de] [1,4]benzoxazine-6-carboxylic acid;(S)-(-)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido [1,2,3-de][1,4]benzoxazine-6-carboxylic acid;(S)-(-)-9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid;(S)-(-)-9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid;(S)-9,10-DIFLUORO-3-METHYL-7-OXO-2,3-DIHYDRO-7H-PYRIDO(1,2,3-DE)(1,4)BENZOXAZINE-6-CARBOXYLIC ACID;6,7-diluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

Suppliers and Price of Levofloxacin Q-Acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Levofloxacin carboxylic acid
10g
$ 523.00

TRC
LevofloxacinCarboxylicAcid(LevofloxacinDifluoroImpurity)
5g
$ 425.00

TCI Chemical
Levofloxacin Q-Acid >98.0%(HPLC)(T)
1g
$ 60.00

TCI Chemical
Levofloxacin Q-Acid >98.0%(HPLC)(T)
5g
$ 180.00

Sigma-Aldrich
Levofloxacin Related Compound B Pharmaceutical Secondary Standard; Certified Reference Material
100 mg
$ 413.00

Sigma-Aldrich
Levofloxacin Related Compound B United States Pharmacopeia (USP) Reference Standard
35mg
$ 1160.00

Sigma-Aldrich
(S)-(?)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid 97%
5g
$ 316.00

Matrix Scientific
(S)-9,10-Difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid 97%
1g
$ 284.00

Matrix Scientific
(S)-9,10-Difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid 97%
5g
$ 1008.00

Chem-Impex
(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid,≥97% ≥97%
5G
$ 338.96

Total 153 raw suppliers

Chemical Property of Levofloxacin Q-Acid Edit

Chemical Property:

Vapor Pressure:3.14E-09mmHg at 25°C
Melting Point:>280 °C
Refractive Index:1.635
Boiling Point:459.2 °C at 760 mmHg
PKA:4.87±0.40(Predicted)
Flash Point:231.5 °C
PSA：68.53000
Density:1.61 g/cm³
LogP:1.93130
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly)
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:281.04996409
Heavy Atom Count:20
Complexity:495

Purity/Quality:

99% ,99.9%, ^*data from raw suppliers

Levofloxacin carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-36/37/3
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1COC2=C3N1C=C(C(=O)C3=CC(=C2F)F)C(=O)O
Isomeric SMILES:C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2F)F)C(=O)O
Uses Levofloxacin intermediate.

Technology Process of Levofloxacin Q-Acid

There total 26 articles about Levofloxacin Q-Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.9%