Fmoc-Phe(4-F)-OH

Base Information Edit

Chemical Name:Fmoc-Phe(4-F)-OH
CAS No.:169243-86-1
Molecular Formula:C₂₄H₂₀FNO₄
Molecular Weight:405.426
Hs Code.:29223990
European Community (EC) Number:671-840-9
DSSTox Substance ID:DTXSID50370321
Nikkaji Number:J2.436.605G
Wikidata:Q72478348
Mol file:169243-86-1.mol

Synonyms:169243-86-1;Fmoc-Phe(4-F)-OH;Fmoc-4-fluoro-L-phenylalanine;Fmoc-L-4-Fluorophenylalanine;FMOC-L-4-Fluorophe;fmoc-4-fluoro-l-phe;fmoc-p-fluoro-phe-oh;(l)-4-fluoro-phenyl-n-fmoc-alanine;(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-fluorophenyl)propanoic acid;fmoc-4-fluoro-phe-oh;fmoc-4-fluoro-phenylalanine;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-fluorophenyl)propanoic acid;Fmoc-L-phe(4-F)-OH;Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-fluoro-;l-3-(4-fluoro-phenyl)-n-fmoc-alanine;fmoc-4-fluoro-l-phe-oh;(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-fluorophenyl)propanoic acid;(s)-2-(((9h-fluoren-9-yl)methoxy)carbonylamino)-3-(4-fluorophenyl)propanoic acid;(s)-n-fmoc-4-fluorophenylalanine;fmoc-pf-l-phe-oh;fmocphe(4f)-oh;MFCD00191197;fmoc-l-phe(4-f);4-fluoro-l-phenylalanine, n-fmoc protected;fmoc-4-fluoro phenylalanine;SCHEMBL119362;FMOC-P-FLUORO-L-PHE-OH;(s)-fmoc-4-fluoro-phenylalanine;N-Fmoc-4-fluoro-L-phenylalanine;DTXSID50370321;IXUMACXMEZBPJG-QFIPXVFZSA-N;l-4-fluoro-phenyl-n-fmoc-alanine;L-FMOC-4-FLUOROPHENYLALANINE;AKOS015908509;AC-7949;AM83347;CS-W009711;HY-W008995;AS-14763;F0902;EN300-314564;Fmoc-Phe(4-F)-OH, >=98.0% (HPLC);J-300406;J-505179;(S)-2-(((9H-fluoren-9-yl)methoxy)carbonyl)propanoic acid;N-(9H-Fluorene-9-ylmethoxycarbonyl)-4-fluoro-L-phenylalanine;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-fluoro-L-phenylalanine;n-alpha-(9-fluorenylmethyloxycarbonyl)-l-4-fluoro-phenylalanine;N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-fluoro-L-phenylalanine;(s)-2-(9h-fluoren-9-ylmethoxycarbonylamino)-3-(4-fluoro-phenyl)-propionic acid

Suppliers and Price of Fmoc-Phe(4-F)-OH

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-4-fluoro-L-phenylalanine
2g
$ 333.00

TRC
Fmoc-Phe(4-F)-OH
250mg
$ 55.00

TCI Chemical
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-fluoro-L-phenylalanine >95.0%(HPLC)(T)
5g
$ 251.00

TCI Chemical
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-fluoro-L-phenylalanine >95.0%(HPLC)(T)
1g
$ 68.00

SynQuest Laboratories
4-Fluoro-L-phenylalanine, N-Fmoc protected
25 g
$ 439.00

SynQuest Laboratories
4-Fluoro-L-phenylalanine, N-Fmoc protected
1 g
$ 69.00

SynQuest Laboratories
4-Fluoro-L-phenylalanine, N-Fmoc protected
5 g
$ 127.00

Sigma-Aldrich
Fmoc-Phe(4-F)-OH Novabiochem?
5 g
$ 377.00

Sigma-Aldrich
Fmoc-Phe(4-F)-OH Novabiochem . CAS 169243-86-1, molar mass 405.42 g/mol., Novabiochem
8522140005
$ 364.00

Sigma-Aldrich
Fmoc-Phe(4-F)-OH Novabiochem?
1 g
$ 93.90

Total 82 raw suppliers

Chemical Property of Fmoc-Phe(4-F)-OH Edit

Chemical Property:

Appearance/Colour:white fluffy powder
Vapor Pressure:1.99E-16mmHg at 25°C
Melting Point:185.4 °C
Boiling Point:623.9 °C at 760 mmHg
PKA:3.75±0.10(Predicted)
Flash Point:331.1 °C
PSA：75.63000
Density:1.317 g/cm³
LogP:4.75100
Storage Temp.:2-8°C
Solubility.:Soluble in Dimethylformamide(DMF).
XLogP3:4.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:405.13763628
Heavy Atom Count:30
Complexity:584

Purity/Quality:

97% ^*data from raw suppliers

Fmoc-4-fluoro-L-phenylalanine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 24/25-22-28-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CC=C(C=C4)F)C(=O)O
Isomeric SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CC4=CC=C(C=C4)F)C(=O)O
Uses 4-Fluoro-N-Fmoc-L-phenylalanine derivative was introduced in collaboration with Yu and coworkers in reflection to a methodology reported in C-H Activation. It is also used as pharmaceutical intermediate. Phenylalanine derivative was introduced in collaboration with Yu and coworkers in reflection to a methodology reported in C-H Activation.

Technology Process of Fmoc-Phe(4-F)-OH

There total 13 articles about Fmoc-Phe(4-F)-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%