(S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine

Base Information

Chemical Name:(S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine
CAS No.:1085492-94-9
Molecular Formula:C₁₈H₂₅NO₄
Molecular Weight:319.401
Hs Code.:

Synonyms:(S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine

Suppliers and Price of (S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine

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Technology Process of (S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine

There total 1 articles about (S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1085493-00-0
C₂₀H₂₉NO₄

: 1085492-94-9
(S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine

Guidance literature:: With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 20 ℃; for 48h; Inert atmosphere;
DOI:10.1055/s-2008-1078280

Reference yield: 97.0%

: 1085492-94-9
(S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1085493-06-6
C₂₄H₃₉NO₄Si

Guidance literature:: With 1H-imidazole; dmap; In dichloromethane; at 20 ℃;
DOI:10.1055/s-2008-1078280

Reference yield: 67.0%

: 1085492-94-9
(S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine

: 1105054-23-6
5-benzyloxymethyl-1-tert-butoxycarbonylpiperidine-3,4-diol

Guidance literature:: (S)-N-tert-butoxycarbonyl-5-hydroxy-3-(benzyloxy)methyl-1,2,5,6-tetrahydropyridine; With borane-THF; In tetrahydrofuran; at 0 - 70 ℃;

With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃;
DOI:10.1002/chem.200801439