(3-methoxy-4-methyl)benzoyl azide

Base Information

• Chemical Name: (3-methoxy-4-methyl)benzoyl azide
• CAS No.: 950508-44-8
• Molecular Formula: C₉H₉N₃O₂
• Molecular Weight: 191.189
• Mol file: 950508-44-8.mol

Synonyms:(3-methoxy-4-methyl)benzoyl azide

Chemical Property of (3-methoxy-4-methyl)benzoyl azide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3-methoxy-4-methyl)benzoyl azide

There total 1 articles about (3-methoxy-4-methyl)benzoyl azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3-methoxy-p-toluic acid (7151-68-0) → (3-methoxy-4-methyl)benzoyl azide (950508-44-8)

Guidance literature:

3-methoxy-p-toluic acid; With thionyl chloride; In chloroform;

With sodium azide; In dichloromethane; water; Further stages.;

DOI:10.1016/j.tetasy.2007.06.004

Reference yield: 87.0%

(3-methoxy-4-methyl)benzoyl azide (950508-44-8) + ethanol (64-17-5) → N-carbethoxy-3-methoxy-4-methyl-benzenamine (105702-85-0)

Guidance literature:

In toluene; for 24h; Heating;

DOI:10.1016/j.tetasy.2007.06.004

Reference yield:

(3-methoxy-4-methyl)benzoyl azide (950508-44-8) → N-allyl-N-carbethoxy-3-methoxy-4-methyl-benzenamine (950508-48-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / toluene / 24 h / Heating

2: 80 percent / NaH / tetrahydrofuran / 24 h / Heating

With sodium hydride; In tetrahydrofuran; toluene; 1: Curtius degradation;

DOI:10.1016/j.tetasy.2007.06.004

upstream raw materials:

3-methoxy-p-toluic acid

Downstream raw materials:

N-carbethoxy-3-methoxy-4-methyl-benzenamine

N-allyl-N-carbethoxy-3-methoxy-4-methyl-benzenamine

N-allyl-N-carbethoxy-2-formyl-5-methoxy-4-methyl-benzenamine

(αR,3aR,9bR)-5-carbethoxy-1-(1-phenyl-2-hydroxyethyl)-7-methoxy-8-methyl-1,3a,4,9b-tetrahydro-3H-isoxazolo[4,3-c]quinoline

Refernces