Technology Process of ((3aS,4R,6R,7S,7aR)-6-Allyl-7-benzyloxy-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-yl)-methanol
There total 6 articles about ((3aS,4R,6R,7S,7aR)-6-Allyl-7-benzyloxy-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-yl)-methanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 23 ℃;
for 2h;
DOI:10.1055/s-2002-33511
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 89 percent / MeONa / methanol / 48 h / 0 °C
2: imidazole / dimethylformamide / 0.5 h / 24 °C
3: CSA / 1.5 h / 24 °C
4: 99 percent / NaI; Bu4NI / tetrahydrofuran / 30 h / 24 °C
5: 100 percent / TBAF / tetrahydrofuran / 2 h / 23 °C
With
1H-imidazole; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; sodium methylate; tetra-(n-butyl)ammonium iodide; sodium iodide;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1055/s-2002-33511
- Guidance literature:
-
Multi-step reaction with 4 steps
1: imidazole / dimethylformamide / 0.5 h / 24 °C
2: CSA / 1.5 h / 24 °C
3: 99 percent / NaI; Bu4NI / tetrahydrofuran / 30 h / 24 °C
4: 100 percent / TBAF / tetrahydrofuran / 2 h / 23 °C
With
1H-imidazole; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; sodium iodide;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1055/s-2002-33511
![((3aS,4R,6R,7S,7aR)-6-Allyl-7-benzyloxy-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethoxy)-tert-butyl-diphenyl-silane](/Databaselist/images/loading.webp)
