Technology Process of 2-(benzylamino)-5,5,5-triphenylpentanoic acid
There total 6 articles about 2-(benzylamino)-5,5,5-triphenylpentanoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-(benzylamino)-5,5,5-triphenylpentanenitrile;
With
hydrogenchloride;
In
1,4-dioxane;
for 48h;
Reflux;
With
methyloxirane;
In
ethanol;
for 0.5h;
Reflux;
DOI:10.1021/jm201195m
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: montmorillonite KSF / dichloromethane / 2 h / 20 °C
2.1: hydrogenchloride / 1,4-dioxane / 48 h / Reflux
2.2: 0.5 h / Reflux
With
hydrogenchloride;
In
1,4-dioxane; dichloromethane;
1.1: Strecker synthesis;
DOI:10.1021/jm201195m
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: n-butyllithium / hexane; dichloromethane / 0 - 20 °C
1.2: 6 h / 20 °C
2.1: sodium tetrahydroborate; sulfuric acid / diethyl ether; diethylene glycol dimethyl ether / 5 h / 20 - 75 °C
3.1: dihydrogen peroxide; sodium hydroxide / water / 6.83 h / 0 - 20 °C
4.1: Dess-Martin periodane / dichloromethane / 3 h / 20 °C
5.1: montmorillonite KSF / dichloromethane / 2 h / 20 °C
6.1: hydrogenchloride / 1,4-dioxane / 48 h / Reflux
6.2: 0.5 h / Reflux
With
hydrogenchloride; sodium tetrahydroborate; n-butyllithium; sulfuric acid; dihydrogen peroxide; Dess-Martin periodane; sodium hydroxide;
In
1,4-dioxane; diethyl ether; hexane; dichloromethane; diethylene glycol dimethyl ether; water;
5.1: Strecker synthesis;
DOI:10.1021/jm201195m
