Technology Process of 2-(benzylamino)-5,5,5-triphenylpentanenitrile
There total 5 articles about 2-(benzylamino)-5,5,5-triphenylpentanenitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
montmorillonite KSF;
In
dichloromethane;
at 20 ℃;
for 2h;
DOI:10.1021/jm201195m
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: n-butyllithium / hexane; dichloromethane / 0 - 20 °C
1.2: 6 h / 20 °C
2.1: sodium tetrahydroborate; sulfuric acid / diethyl ether; diethylene glycol dimethyl ether / 5 h / 20 - 75 °C
3.1: dihydrogen peroxide; sodium hydroxide / water / 6.83 h / 0 - 20 °C
4.1: Dess-Martin periodane / dichloromethane / 3 h / 20 °C
5.1: montmorillonite KSF / dichloromethane / 2 h / 20 °C
With
sodium tetrahydroborate; n-butyllithium; sulfuric acid; dihydrogen peroxide; Dess-Martin periodane; sodium hydroxide;
In
diethyl ether; hexane; dichloromethane; diethylene glycol dimethyl ether; water;
5.1: Strecker synthesis;
DOI:10.1021/jm201195m
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium tetrahydroborate; sulfuric acid / diethyl ether; diethylene glycol dimethyl ether / 5 h / 20 - 75 °C
2: dihydrogen peroxide; sodium hydroxide / water / 6.83 h / 0 - 20 °C
3: Dess-Martin periodane / dichloromethane / 3 h / 20 °C
4: montmorillonite KSF / dichloromethane / 2 h / 20 °C
With
sodium tetrahydroborate; sulfuric acid; dihydrogen peroxide; Dess-Martin periodane; sodium hydroxide;
In
diethyl ether; dichloromethane; diethylene glycol dimethyl ether; water;
4: Strecker synthesis;
DOI:10.1021/jm201195m
