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10-Hydroxy-2-decenoic acid

Base Information Edit
  • Chemical Name:10-Hydroxy-2-decenoic acid
  • CAS No.:14113-05-4
  • Molecular Formula:C10H18O3
  • Molecular Weight:186.251
  • Hs Code.:29181990
  • European Community (EC) Number:808-119-7
  • NSC Number:87516
  • UNII:76B519G7TJ
  • DSSTox Substance ID:DTXSID601045504
  • Nikkaji Number:J565.209J,J838.856C
  • Wikipedia:Queen_bee_acid
  • Wikidata:Q16908844
  • Metabolomics Workbench ID:1363
  • Mol file:14113-05-4.mol
10-Hydroxy-2-decenoic acid

Synonyms:10-HDEC;10-hydroxy-2-decenoic acid;10-hydroxy-2-decenoic acid, (E)-isomer;10-hydroxy-2-decenoic acid, monopotassium salt;10-hydroxy-2-decenoic acid, monosodium salt;10-hydroxy-2-decenoic acid, sodium salt;Hydroxydecine

Suppliers and Price of 10-Hydroxy-2-decenoic acid
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 10-Hydroxy-2-decenoicacid
  • 50mg
  • $ 45.00
  • TCI Chemical
  • trans-10-Hydroxy-2-decenoic Acid >97.0%(GC)(T)
  • 200mg
  • $ 60.00
  • TCI Chemical
  • trans-10-Hydroxy-2-decenoic Acid >97.0%(GC)(T)
  • 1g
  • $ 205.00
  • Sigma-Aldrich
  • 10-Hydroxy-trans-2-decenoic acid phyproof? Reference Substance
  • 10 mg
  • $ 245.00
  • JR MediChem
  • 10-Hydroxy-2-decenoicacid 98%
  • 20mg
  • $ 300.00
  • DC Chemicals
  • 10-Hydroxy-2-decenoicacid >98%,StandardReferencesGrade
  • 20 mg
  • $ 280.00
  • CSNpharm
  • Royaljellyacid
  • 10mg
  • $ 33.00
  • Cayman Chemical
  • 10-HDA ≥98%
  • 1g
  • $ 320.00
  • Cayman Chemical
  • 10-HDA ≥98%
  • 100mg
  • $ 78.00
  • Cayman Chemical
  • 10-HDA ≥98%
  • 500mg
  • $ 199.00
Total 150 raw suppliers
Chemical Property of 10-Hydroxy-2-decenoic acid Edit
Chemical Property:
  • Vapor Pressure:6.5E-06mmHg at 25°C 
  • Melting Point:64.0 to 68.0 °C 
  • Refractive Index:1.465 
  • Boiling Point:339.2 °C at 760 mmHg 
  • PKA:4.78±0.10(Predicted) 
  • Flash Point:173.1 °C 
  • PSA:57.53000 
  • Density:1.038 g/cm3 
  • LogP:1.96010 
  • Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C 
  • XLogP3:2.2
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:8
  • Exact Mass:186.125594432
  • Heavy Atom Count:13
  • Complexity:152
Purity/Quality:

99% *data from raw suppliers

10-Hydroxy-2-decenoicacid *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
  • Safety Statements: 24/25 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C(CCCC=CC(=O)O)CCCO
  • Isomeric SMILES:C(CCC/C=C/C(=O)O)CCCO
  • Description 10-HDA is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees. 10-HDA has longevity-promoting effects in C. elegans at a concentration of 25 μM. It down-regulates matrix metalloproteinases (MMPs) in rheumatoid arthritis synovial fibroblasts at a concentration of 1.25 nM and inhibits VEGF-induced angiogenesis in HUVECs at 500 μM. 10-HDA also facilitates differentiation of neurons from neural stem/progenitor cells and promotes collagen production by skin fibroblasts at concentrations of 100 μM and 1.5 mM, respectively.
Technology Process of 10-Hydroxy-2-decenoic acid

There total 52 articles about 10-Hydroxy-2-decenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With water; sodium hydroxide; In ethanol; at 60 ℃; for 4h;
DOI:10.1007/s10600-014-0969-x
Guidance literature:
With sodium hydroxide; at 20 ℃; for 4h; Time;
Guidance literature:
With potassium hydroxide; water; In ethanol; for 8h;
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