HYDROXYDEC-2-ENOIC ACID ETHYL ESTER, (E)-10-(SH)

Base Information

• Chemical Name: HYDROXYDEC-2-ENOIC ACID ETHYL ESTER, (E)-10-(SH)
• CAS No.: 57221-93-9
• Molecular Formula: C12H22O3
• Molecular Weight: 214.305
• Mol file: 57221-93-9.mol

Synonyms:10-Hydroxy-dec-2t-ensaeure-ethylester;10-hydroxy 8-decenoic acid ethyl ester;10-Hydroxy-2-decensaeureethylester;2-Decenoic acid,10-hydroxy-,ethyl ester;Ethyl-10-hydroxy-trans-2-decenoat;

Chemical Property of HYDROXYDEC-2-ENOIC ACID ETHYL ESTER, (E)-10-(SH)

Chemical Property:

• PSA: 46.53000
• LogP: 2.43860

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of HYDROXYDEC-2-ENOIC ACID ETHYL ESTER, (E)-10-(SH)

There total 11 articles about HYDROXYDEC-2-ENOIC ACID ETHYL ESTER, (E)-10-(SH) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

diethoxyphosphoryl-acetic acid ethyl ester (867-13-0) + 8-hydroxyoctanal (22054-14-4) → 10-hydroxy 8-decenoic acid ethyl ester (57221-93-9)

Guidance literature:

With potassium carbonate; In water; for 20h;

Reference yield: 79.0%

ethyl (E)-10-(2-tetrahydropyranyloxy)-2-decenoate (57221-92-8) → 10-hydroxy 8-decenoic acid ethyl ester (57221-93-9)

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; for 1h; Heating;

DOI:10.1246/bcsj.57.426

Reference yield:

8-tetrahydropyranyloxyoctanal (57221-80-4) → 10-hydroxy 8-decenoic acid ethyl ester (57221-93-9)

Guidance literature:

Multi-step reaction with 2 steps

2: 79 percent / p-toluenesulfonic acid / ethanol / 1 h / Heating

With toluene-4-sulfonic acid; In ethanol;

DOI:10.1246/bcsj.57.426

upstream raw materials:

10-hydroxydecanoic acid ethyl ester

diethoxyphosphoryl-acetic acid ethyl ester

8-hydroxyoctanal

ethyl (2E)-2,9-decadienoate

Downstream raw materials:

10-hydroxy-2-decenoic acid

(E)-10-hydroxy-dec-2-enoic acid

Refernces

• 1、 Trehen, I R,Vig, Rakesh,Singh, Vasundhara,Sharma, Sushma,Kad, G L. "Synthesis of (E)-9-oxo-2-decenoic acid and (E)-10-hydroxy-2-decenoic acid". . p. 257 - 259. Retrieved 2007/10/02.
• 2、 Villieras, J.,Rambaud, M.,Graff, M.. "WITTIG-HORNER REACTION IN HETEROGENOUS MEDIA VII. A NEW STRATEGY FOR THE TOTAL SYNTHESIS OF THE ROYAL JELLY ACID AND THE QUEEN SUBSTANCE OF HONEY-BEE". . p. 569 - 580. Retrieved 2007/10/02.