(benzyloxycarbonylamino)(2-(tert-butoxycarbonyl)-1-phenylhydrazinyl)di(pyrrolidin-1-yl)phosphonium chloride

Base Information

• Chemical Name: (benzyloxycarbonylamino)(2-(tert-butoxycarbonyl)-1-phenylhydrazinyl)di(pyrrolidin-1-yl)phosphonium chloride
• CAS No.: 1542782-32-0
• Molecular Formula: C₂₇H₃₈N₅O₄P*ClH
• Molecular Weight: 564.065
• Mol file: 1542782-32-0.mol

Synonyms:(benzyloxycarbonylamino)(2-(tert-butoxycarbonyl)-1-phenylhydrazinyl)di(pyrrolidin-1-yl)phosphonium chloride

Chemical Property of (benzyloxycarbonylamino)(2-(tert-butoxycarbonyl)-1-phenylhydrazinyl)di(pyrrolidin-1-yl)phosphonium chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (benzyloxycarbonylamino)(2-(tert-butoxycarbonyl)-1-phenylhydrazinyl)di(pyrrolidin-1-yl)phosphonium chloride

There total 1 articles about (benzyloxycarbonylamino)(2-(tert-butoxycarbonyl)-1-phenylhydrazinyl)di(pyrrolidin-1-yl)phosphonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyloxycarbonyl azide (3422-03-5) + bis(N,N-pyrrolidino) chlorophosphine (63135-66-0) + tert-butyl 2-phenylhydrazine-1-carboxylate (42116-43-8) → (benzyloxycarbonylamino)(2-(tert-butoxycarbonyl)-1-phenylhydrazinyl)di(pyrrolidin-1-yl)phosphonium chloride (1542782-32-0)

Guidance literature:

bis(N,N-pyrrolidino) chlorophosphine; tert-butyl 2-phenylhydrazine-1-carboxylate; With triethylamine; In toluene; at 0 - 20 ℃; for 2h; Inert atmosphere;

benzyloxycarbonyl azide; In toluene; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1055/s-0033-1340058

Reference yield: 95.0%

(benzyloxycarbonylamino)(2-(tert-butoxycarbonyl)-1-phenylhydrazinyl)di(pyrrolidin-1-yl)phosphonium chloride (1542782-32-0) → amino(2-(tert-butoxycarbonyl)-1-phenylhydrazinyl)di(pyrrolidin-1-yl)phosphonium chloride (1542782-36-4)

Guidance literature:

With triethylsilane; triethylamine; palladium dichloride; In dichloromethane; Inert atmosphere; Reflux;

DOI:10.1055/s-0033-1340058

upstream raw materials:

benzyloxycarbonyl azide

bis(N,N-pyrrolidino) chlorophosphine

tert-butyl 2-phenylhydrazine-1-carboxylate

Downstream raw materials:

amino(2-(tert-butoxycarbonyl)-1-phenylhydrazinyl)di(pyrrolidin-1-yl)phosphonium chloride