(E)-3-(p-Tolylsulfinyl)acrylic acid methyl ester

Base Information

Chemical Name:(E)-3-(p-Tolylsulfinyl)acrylic acid methyl ester
CAS No.:184377-59-1
Molecular Formula:C₁₁H₁₂O₃S
Molecular Weight:224.28
Hs Code.:
DSSTox Substance ID:DTXSID301216427
Nikkaji Number:J1.928.549I,J1.365.483B

Synonyms:184377-59-1;DTXSID301216427;(E)-3-(p-Tolylsulfinyl)acrylic acid methyl ester;3-(4-Methylphenylsulfinyl)acrylic acid methyl ester;Methyl (2E)-3-[(4-methylphenyl)sulfinyl]-2-propenoate

Suppliers and Price of (E)-3-(p-Tolylsulfinyl)acrylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-3-(p-Tolylsulfinyl)acrylic acid methyl ester

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:224.05071541
Heavy Atom Count:15
Complexity:265

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)C=CC(=O)OC
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)/C=C/C(=O)OC

Technology Process of (E)-3-(p-Tolylsulfinyl)acrylic acid methyl ester

There total 3 articles about (E)-3-(p-Tolylsulfinyl)acrylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 922-67-8
propynoic acid methyl ester

: 383911-55-5
3,3-dimethyl-1-butynyl p-tolyl sulfoxide

: 184377-59-1
E-2-carbomethoxyethenyl p-tolyl sulfoxide

Guidance literature:: With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; diethylzinc; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 4.25h;
DOI:10.1021/jo034108j

Reference yield:

: 1277172-77-6
methyl 3-(p-tolylthio)acrylate

: Z-2-carbomethoxyethenyl p-tolyl sulfoxide

: 184377-59-1
E-2-carbomethoxyethenyl p-tolyl sulfoxide

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -78 - -40 ℃;
DOI:10.1039/b917217c

Reference yield:

: (3,3-dimethylbut-1-yn-1-yl)(p-tolyl)sulfane

: 184377-59-1
E-2-carbomethoxyethenyl p-tolyl sulfoxide

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / aq. m-CPBA / CH₂Cl₂ / 0.5 h / 0 °C

2: 87 percent / Et₂Zn; Pd₂(dba)3*CHCl₃ / hexane; tetrahydrofuran / 4.25 h / -78 - 20 °C

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; diethylzinc; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jo034108j