methyl 3-phenyl-2-({2-[4-(2-methylpropyl)phenyl]propanoyl}amino)propanoate

Base Information

Chemical Name:methyl 3-phenyl-2-({2-[4-(2-methylpropyl)phenyl]propanoyl}amino)propanoate
CAS No.:1339077-65-4
Molecular Formula:C₂₃H₂₉NO₃
Molecular Weight:367.488
Hs Code.:

Synonyms:methyl 3-phenyl-2-({2-[4-(2-methylpropyl)phenyl]propanoyl}amino)propanoate

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Chemical Property of methyl 3-phenyl-2-({2-[4-(2-methylpropyl)phenyl]propanoyl}amino)propanoate

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Technology Process of methyl 3-phenyl-2-({2-[4-(2-methylpropyl)phenyl]propanoyl}amino)propanoate

There total 5 articles about methyl 3-phenyl-2-({2-[4-(2-methylpropyl)phenyl]propanoyl}amino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 115588-20-0
(2S)-2-(4-isobutylphenyl)-propionyl chloride

: 1339077-65-4
methyl 3-phenyl-2-({2-[4-(2-methylpropyl)phenyl]propanoyl}amino)propanoate

Guidance literature:: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride; With sodium hydroxide; In water; at 20 ℃; for 0.5h;

(2S)-2-(4-isobutylphenyl)-propionyl chloride; In water; at 2 - 8 ℃;
DOI:10.3109/14756366.2010.548327

Reference yield: 85.0%

: 2577-90-4
methyl (2S)-2-amino-3-phenylpropanoate

: 115588-20-0
(2S)-2-(4-isobutylphenyl)-propionyl chloride

: 1339077-65-4
methyl 3-phenyl-2-({2-[4-(2-methylpropyl)phenyl]propanoyl}amino)propanoate

Guidance literature:: methyl (2S)-2-amino-3-phenylpropanoate; With sodium hydroxide; In water; at 20 ℃; for 0.5h;

(2S)-2-(4-isobutylphenyl)-propionyl chloride; In water; at 10 ℃;
DOI:10.1007/s00044-011-9866-z

Reference yield:

: 51146-56-6,58560-75-1
(S)-ibuprofen

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 1339077-65-4
methyl 3-phenyl-2-({2-[4-(2-methylpropyl)phenyl]propanoyl}amino)propanoate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 6h;
DOI:10.1002/anie.201703461