N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutoxybenzyl)carbamide hydrochloride

Base Information

Chemical Name:N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutoxybenzyl)carbamide hydrochloride
CAS No.:639861-37-3
Molecular Formula:C₂₉H₄₀FN₃O₄*ClH
Molecular Weight:550.114
Hs Code.:

Synonyms:N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutoxybenzyl)carbamide hydrochloride

Suppliers and Price of N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutoxybenzyl)carbamide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutoxybenzyl)carbamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutoxybenzyl)carbamide hydrochloride

There total 4 articles about N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutoxybenzyl)carbamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutyloxybenzyl)carbamide

: 639861-37-3
N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutoxybenzyl)carbamide hydrochloride

Guidance literature:: With hydrogenchloride;

Reference yield:

: 639863-76-6
N-(4-fluorobenzyl)-N-[1-(trifluoroacetyl)piperidin-4-yl]-N'-(4-isobutyloxybenzyl)carbamide

: 639861-37-3
N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutoxybenzyl)carbamide hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / methanol / 4 h

2: potassium carbonate; sodium iodide / acetonitrile / 20 h / Heating / reflux

3: hydrogenchloride

With hydrogenchloride; potassium carbonate; sodium iodide; In methanol; acetonitrile;

Reference yield:

: 2-(4-isobutyloxyphenyl)acetic acid methyl ester

: 639861-37-3
N-{1-[2-(1,3-dioxolan-2-yl)ethyl]piperidin-4-yl}-N-(4-fluorobenzyl)-N'-(4-isobutoxybenzyl)carbamide hydrochloride

Guidance literature:: Multi-step reaction with 6 steps

1.1: potassium hydroxide; water / methanol / 20 °C

2.1: Proton Sponge_.(TM). / tetrahydrofuran / 0.25 h

2.2: 24 h / -18 - 20 °C / Heating / reflux

3.1: dichloromethane / 20 h

4.1: potassium carbonate / methanol / 4 h

5.1: potassium carbonate; sodium iodide / acetonitrile / 20 h / Heating / reflux

6.1: hydrogenchloride

With hydrogenchloride; potassium hydroxide; water; potassium carbonate; sodium iodide; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;