2-Chloro-5-nitro-benzamine

Base Information

• Chemical Name: 2-Chloro-5-nitro-benzamine
• CAS No.: 6283-25-6
• Molecular Formula: C6H5ClN2O2
• Molecular Weight: 172.571
• Hs Code.: 29215900
• European Community (EC) Number: 228-498-7
• NSC Number: 7791
• UNII: PO198891S5
• DSSTox Substance ID: DTXSID6038827
• Nikkaji Number: J55.210K
• Wikidata: Q27286657
• ChEMBL ID: CHEMBL325115
• Mol file: 6283-25-6.mol

Synonyms:Aniline,2-chloro-5-nitro- (7CI,8CI);1-Amino-2-chloro-5-nitrobenzene;2-Chloro-5-nitrobenzenamine;2-Chloro-5-nitrophenylamine;5-Nitro-2-chloroaniline;6-Chloro-3-nitroaniline;Benzenamine,2-chloro-5-nitro-;

Chemical Property of 2-Chloro-5-nitro-benzamine

Chemical Property:

• Appearance/Colour: yellow powder
• Vapor Pressure: 0.00046mmHg at 25°C
• Melting Point: 118-120 °C(lit.)
• Refractive Index: 1.646
• Boiling Point: 314.6 °C at 760 mmHg
• PKA: 0.60±0.10(Predicted)
• Flash Point: 144.1 °C
• PSA: 71.84000
• Density: 1.494 g/cm³
• LogP: 2.93480
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 172.0039551
• Heavy Atom Count: 11
• Complexity: 159

Purity/Quality:

98% ^*data from raw suppliers

2-Chloro-5-nitroaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T+, N
• Hazard Codes: T+,N
• Statements: 26/27/28-33-51/53-50/53
• Safety Statements: 28-36/37-45-61-28A-60-13

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Nitroanilines
• Canonical SMILES: C1=CC(=C(C=C1[N+](=O)[O-])N)Cl

Technology Process of 2-Chloro-5-nitro-benzamine

There total 16 articles about 2-Chloro-5-nitro-benzamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

o-chloroaniline (95-51-2) → H2NC6H3(Cl)NO2 (6283-25-6)

Guidance literature:

With sulfuric acid; uronium nitrate; at 0 - 10 ℃; for 1h;

Reference yield: 70.0%

2-nitro-4-amino-5-chlorobenzoic acid (136833-46-0) → H2NC6H3(Cl)NO2 (6283-25-6)

Guidance literature:

With hydrogenchloride; Heating;

Reference yield: 61.0%

1-chloro-2,4-dinitro-benzene (97-00-7) → 4-Chloro-3-nitroaniline (635-22-3) + H2NC6H3(Cl)NO2 (6283-25-6)

Guidance literature:

With hydrogen; iron; acetic acid; palladium dichloride; In ethanol; at 20 - 25 ℃; under 258.6 - 2327.2 Torr;

DOI:10.1016/S0040-4039(00)97008-4

upstream raw materials:

2-chloro-5-nitro-benzamide

N-(o-chlorophenyl)-phthalimide

N-(2-chlorophenyl)acetamide

o-chloroaniline

Downstream raw materials:

furan-2-carboxylic acid-(2-chloro-5-nitro-anilide)

N-(2-chloro-5-nitrophenyl)formamide

2-amino-4-nitrobenzenethiol

5,5'-dinitro-2,2'-sulfanediyl-di-aniline