cyanoester

Base Information

• Chemical Name: cyanoester
• CAS No.: 40878-08-8
• Molecular Formula: C₁₂H₁₁Cl₂NO₂
• Molecular Weight: 272.131
• Mol file: 40878-08-8.mol

Synonyms:cyanoester

Chemical Property of cyanoester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cyanoester

There total 2 articles about cyanoester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

diethyl 2-(3,4-dichlorobenzylidene)malonate (40878-09-9) + potassium cyanide (151-50-8) → cyanoester (40878-08-8)

Guidance literature:

In ethanol; water; at 70 ℃; stirring overnight at 70 deg C;

DOI:10.1080/00397919808004439

Reference yield:

3,4-dichlorobenzaldehyde (6287-38-3) → cyanoester (40878-08-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / piperidine; benzoic acid / benzene / refluxing overnight under an argon atmosphere with Dean-Stark trap

2: 70 percent / ethanol; H₂O / 70 °C / stirring overnight at 70 deg C

piperidine; benzoic acid; In ethanol; water; benzene; 1: Condensation / 2: Cyanidation;

DOI:10.1080/00397919808004439

Reference yield: 74.0%

cyanoester (40878-08-8) → cyanoalcohol (213380-60-0)

Guidance literature:

With sodium tetrahydroborate; n-butyllithium; Diisobutylaluminium hydride(1 M solution in tetrahydrofuran, 4.9 mL, 4.9 mmol); In tetrahydrofuran; ethanol; hexane; at -78 - 0 ℃; for 4h; warming to room temperature over 1 h;

DOI:10.1080/00397919808004439

upstream raw materials:

diethyl 2-(3,4-dichlorobenzylidene)malonate

potassium cyanide

3,4-dichlorobenzaldehyde

Downstream raw materials:

cyanoalcohol

3-arylbutanolide

selenide

Refernces