(R)-1-(benzyloxy)-8-(tert-butyldimethylsilyloxy)-6-methyleneoct-3-yn-2-ol

Base Information

Chemical Name:(R)-1-(benzyloxy)-8-(tert-butyldimethylsilyloxy)-6-methyleneoct-3-yn-2-ol
CAS No.:1268368-82-6
Molecular Formula:C₂₂H₃₄O₃Si
Molecular Weight:374.596
Hs Code.:

Synonyms:(R)-1-(benzyloxy)-8-(tert-butyldimethylsilyloxy)-6-methyleneoct-3-yn-2-ol

Suppliers and Price of (R)-1-(benzyloxy)-8-(tert-butyldimethylsilyloxy)-6-methyleneoct-3-yn-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (R)-1-(benzyloxy)-8-(tert-butyldimethylsilyloxy)-6-methyleneoct-3-yn-2-ol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of (R)-1-(benzyloxy)-8-(tert-butyldimethylsilyloxy)-6-methyleneoct-3-yn-2-ol

There total 1 articles about (R)-1-(benzyloxy)-8-(tert-butyldimethylsilyloxy)-6-methyleneoct-3-yn-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 85428-24-6
(R)-4-benzyloxy-3-hydroxy-1-butyne

: 605664-46-8
2-(chloromethyl)-4-(tert-butyldimethylsilyloxy)-1-butene

: 1268368-82-6
(R)-1-(benzyloxy)-8-(tert-butyldimethylsilyloxy)-6-methyleneoct-3-yn-2-ol

Guidance literature:: (R)-4-benzyloxy-3-hydroxybut-1-yne; With copper(l) iodide; tetrabutylammomium bromide; potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h; Inert atmosphere;

2-(chloromethyl)-4-(tert-butyldimethylsilyloxy)-1-butene; In N,N-dimethyl-formamide; at 20 ℃; for 48h; Inert atmosphere;
DOI:10.1021/ol200203k

Reference yield:

: 1268368-82-6
(R)-1-(benzyloxy)-8-(tert-butyldimethylsilyloxy)-6-methyleneoct-3-yn-2-ol

: C₂₂H₃₆O₃Si

Guidance literature:: With quinoline; hydrogen; In methanol; for 72h; under 760.051 Torr;
DOI:10.1021/ol200203k

Reference yield:

: 1268368-82-6
(R)-1-(benzyloxy)-8-(tert-butyldimethylsilyloxy)-6-methyleneoct-3-yn-2-ol

: C₂₂H₃₆O₃Si

Guidance literature:: With cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate; dimethyl(ethoxy)silane; In dichloromethane; at 0 - 20 ℃; for 0.25h; Inert atmosphere;
DOI:10.1021/ol200203k