Tetrabutylammonium hydroxide

Base Information

• Chemical Name: Tetrabutylammonium hydroxide
• CAS No.: 2052-49-5
• Deprecated CAS: 107716-44-9,151883-00-0,151883-00-0
• Molecular Formula: C16H36N.OH
• Molecular Weight: 259.476
• Hs Code.: 29239000
• European Community (EC) Number: 218-147-6
• UNII: 68I858J9S1
• DSSTox Substance ID: DTXSID8062155
• Wikipedia: Tetrabutylammonium_hydroxide
• Wikidata: Q908825
• ChEMBL ID: CHEMBL1078154
• Mol file: 2052-49-5.mol

Synonyms:Bu(4)NBr;tetra-n-butylammonium dodecylsulfate;tetra-n-butylammonium hexafluorophosphate;tetrabutylammonium;tetrabutylammonium azide;tetrabutylammonium bromide;tetrabutylammonium chloride;tetrabutylammonium cyanide;tetrabutylammonium fluoride;tetrabutylammonium hydrogen sulfate;tetrabutylammonium hydroxide;tetrabutylammonium iodide;tetrabutylammonium monophosphate;tetrabutylammonium nitrate;tetrabutylammonium perchlorate;tetrabutylammonium sulfate;tetrabutylammonium sulfate (1:1), sodium salt

Chemical Property of Tetrabutylammonium hydroxide

Chemical Property:

• Appearance/Colour: Aqueous solution
• Vapor Pressure: 2.3 kPa (@ 20°C)
• Melting Point: 27-30 °C(lit.)
• Refractive Index: 1.4
• Boiling Point: 100 °C
• Flash Point: 7 °C
• PSA: 23.06000
• Density: 0.995 g/cm³
• LogP: 4.82680
• Storage Temp.: 2-8°C
• Sensitive.: Air Sensitive/Hygroscopic
• Solubility.: Miscible with organic solvents.
• Water Solubility.: Soluble in water, methanol.
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 12
• Exact Mass: 259.287514804
• Heavy Atom Count: 18
• Complexity: 116

Purity/Quality:

99% ^*data from raw suppliers

Tetrabutylammonium Hydroxide (10% in Water)[Reagent for Ion-Pair Chromatography] ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T, F, C
• Hazard Codes: C,T,F,Xn
• Statements: 34-36/38-23/24/25-11-67-39/23/24/25-36-65-63-38-48/20-35-20/21/22-10-68/20/21/22
• Safety Statements: 7-16-26-36/37/39-45-36/37-62-27

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Quaternary Amines
• Canonical SMILES: CCCC[N+](CCCC)(CCCC)CCCC.[OH-]
• Uses: TBAOH may be used as an ion-pairing reagent in mobile phase preparation for reverse phase ion-pair high performance liquid chromatography during chromium (III) and chromium (VI) determination.

Technology Process of Tetrabutylammonium hydroxide

There total 11 articles about Tetrabutylammonium hydroxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

tetrabutylammomium bromide (1643-19-2) → tetra(n-butyl)ammonium hydroxide (2052-49-5)

Guidance literature:

With potassium hydroxide; In dichloromethane; at 20 ℃; for 10h;

DOI:10.1021/jp3015386

Reference yield: 71.0%

7-[(2E)-2-(2,3-dihydro-1H-inden-1-ylidene)ethyl]-8-([dimethyl(1,1,2-trimethylpropyl)silyl]oxy)-n,n,2,3-tetramethylimidazo[1,2-a]pyridine-6-carboxamide (1033762-44-5) + tetrabutyl ammonium fluoride (429-41-4) → 7-[(2E)-2-(2,3-dihydro-1H-inden-1-ylidene)ethyl]-8-hydroxy-n,n,2,3-tetramethylimidazo[1,2-a]pyridine-6-carboxamide (1033762-35-4) + tetra(n-butyl)ammonium hydroxide (2052-49-5)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/j.bmc.2008.10.055

Reference yield:

tetrabutyl-ammonium chloride (1112-67-0) → tetra(n-butyl)ammonium hydroxide (2052-49-5)

Guidance literature:

With (Cy₃P)2Pd(Ph)(OH); water; In tetrahydrofuran; at 20 ℃; Equilibrium constant; Inert atmosphere; Sealed vial;

DOI:10.1021/ja1108326

upstream raw materials:

tetrabutylammomium bromide

tetra-(n-butyl)ammonium iodide

7-[(2E)-2-(2,3-dihydro-1H-inden-1-ylidene)ethyl]-8-([dimethyl(1,1,2-trimethylpropyl)silyl]oxy)-n,n,2,3-tetramethylimidazo[1,2-a]pyridine-6-carboxamide

tetrabutyl ammonium fluoride

Downstream raw materials:

1-butylene

tetrabutylammoniun azide

acetophenone

1,1-diphenylethanol

Refernces

• 1、 Li, Hongxia,Liu, Bing,Qin, Yaru,Shi, Chenglong,Song, Guixiu. "Solvent extraction of lithium from aqueous solution using an ammonium ionic liquid". . . Retrieved 2020.
• 2、 Rouch, Anne,Castellan, Tessa,Fabing, Isabelle,Saffon, Nathalie,Rodriguez, Jean,Constantieux, Thierry,Plaquevent, Jean-Christophe,Genisson, Yves. "Tartrate-based ionic liquids: Unified synthesis and characterisation". . p. 413 - 426. Retrieved 2013.
• 3、 -. "Synthesis method of N-hydroxymethyl acrylamide". Paragraph 0038-0040. . Retrieved 2021/06/12.