Syntheses of the phosphodiesterase-4 inhibitors [11C]Ro 20-1724, R-, R/S- and S-[11C]rolipram

DOI: 10.1002/jlcr.465

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 373 - 384 (2001)

Update date:2022-09-26

Topics:

Authors:

Dasilva, Jean N.

Lourenco, Celia M.

Wilson, Alan A.

Houle, Sylvain

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Article abstract of DOI:10.1002/jlcr.465

The high affinity and selective cAMP-specific phosphodiesterase-4 inhibitors Ro 20-1724, R-, R/S- and S-rolipram were labeled with ¹¹C by O-[¹¹C]methylation of their respective phenolic precursors using [¹¹C]methyl iodide.

Full text of DOI:10.1002/jlcr.465

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