Technology Process of m-tetrahydropyranyloxyphenylacetone
There total 5 articles about m-tetrahydropyranyloxyphenylacetone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1) NaH / 1) paraffin oil; 2) reflux, 10 min
2: 44 percent / sulphuric acid (50percent) / 0.5 h / 120 - 130 °C
3: 78 percent / boron tribromide / CH2Cl2 / 1 h at -70 deg C, then within 2 h to room temp.
4: 50.6 percent / conc. aq. HCl / 24 h / Ambient temperature
With
hydrogenchloride; sulfuric acid; boron tribromide; sodium hydride;
In
dichloromethane;
DOI:10.1039/P19800001555
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 78 percent / boron tribromide / CH2Cl2 / 1 h at -70 deg C, then within 2 h to room temp.
2: 50.6 percent / conc. aq. HCl / 24 h / Ambient temperature
With
hydrogenchloride; boron tribromide;
In
dichloromethane;
DOI:10.1039/P19800001555
