2-(3-methyl-1H-indol-1-yl)-1-phenylethanone

Base Information

Chemical Name:2-(3-methyl-1H-indol-1-yl)-1-phenylethanone
CAS No.:80884-56-6
Molecular Formula:C₁₇H₁₅NO
Molecular Weight:249.312
Hs Code.:
DSSTox Substance ID:DTXSID501322876
ChEMBL ID:CHEMBL1410397

Synonyms:80884-56-6;2-(3-methyl-1H-indol-1-yl)-1-phenylethanone;2-(3-methyl-1H-indol-1-yl)-1-phenylethan-1-one;phenacylskatole;2-(3-methylindol-1-yl)-1-phenylethanone;2-(3-Methyl-indol-1-yl)-1-phenyl-ethanone;Cambridge id 5315243;MLS001210574;SCHEMBL6224417;CHEMBL1410397;DTXSID501322876;HMS1580I10;HMS2837A04;STK835320;AKOS000630341;SMR000513545;VU0013646-1;AB00080330-01;SR-01000395597;SR-01000395597-1;F1011-0497

Suppliers and Price of 2-(3-methyl-1H-indol-1-yl)-1-phenylethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(3-methyl-1H-indol-1-yl)-1-phenylethanone

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:249.115364102
Heavy Atom Count:19
Complexity:321

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CN(C2=CC=CC=C12)CC(=O)C3=CC=CC=C3

Technology Process of 2-(3-methyl-1H-indol-1-yl)-1-phenylethanone

There total 9 articles about 2-(3-methyl-1H-indol-1-yl)-1-phenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 163158-85-8
1-phenacylskatole ethyleneketal

: 80884-56-6
2-(3-methyl-1H-indol-1-yl)-1-phenylethanone

Guidance literature:: With hydrogenchloride; In methanol; for 5h; Heating;
DOI:10.1007/BF01165026

Reference yield: 45.0%

: 83-34-1
3-Methylindole

: 70-11-1
α-bromoacetophenone

: 80884-56-6
2-(3-methyl-1H-indol-1-yl)-1-phenylethanone

Guidance literature:: 3-Methylindole; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; Inert atmosphere;

α-bromoacetophenone; In N,N-dimethyl-formamide; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/chem.201301057

Reference yield:

: 83-34-1
3-Methylindole

: 1-bromo-2,4-diphenylbut-3-yn-2-ol

: 80884-56-6
2-(3-methyl-1H-indol-1-yl)-1-phenylethanone

Guidance literature:: 3-Methylindole; With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 2h; Inert atmosphere;

1-bromo-2,4-diphenylbut-3-yn-2-ol; In dimethyl sulfoxide; at 20 ℃; Inert atmosphere;
DOI:10.1021/acs.joc.1c00010