6A,6B,6C,6D,6E,6F,6G-Heptakis-O-(2-hydroxypropyl)-beta-cyclodextrin

Base Information

• Chemical Name: 6A,6B,6C,6D,6E,6F,6G-Heptakis-O-(2-hydroxypropyl)-beta-cyclodextrin
• CAS No.: 128446-35-5
• Molecular Formula: Unspecified
• Molecular Weight: 1541.54000
• Hs Code.: 29400090
• European Community (EC) Number: 603-269-8
• Mol file: 128446-35-5.mol

Synonyms:2 Hydroxypropyl beta cyclodextrin;2 hydroxypropyl-beta-cyclodextrin;2-hydroxypropyl-beta-cyclodextrin;beta Hydroxypropylcyclodextrin;beta-hydroxypropylcyclodextrin;Betadex, Hydroxypropyl;HP-beta-CD;HPbetaCD;Hydroxypropyl beta cyclodextrin;Hydroxypropyl Betadex;hydroxypropyl-beta-cyclodextrin

Chemical Property of 6A,6B,6C,6D,6E,6F,6G-Heptakis-O-(2-hydroxypropyl)-beta-cyclodextrin

Chemical Property:

• Appearance/Colour: white powder
• Melting Point: 278oC (dec.)
• Refractive Index: 125 ° (C=1, H2O)
• Boiling Point: 400℃
• PSA: 618.66000
• Density: 1.05 at 20.3℃
• LogP: -12.39490
• Storage Temp.: 2-8°C
• Solubility.: H2O: 45 % (w/v)
• Water Solubility.: Soluble in water.
• XLogP3: -13
• Hydrogen Bond Donor Count: 21
• Hydrogen Bond Acceptor Count: 42
• Rotatable Bond Count: 28
• Exact Mass: 1540.6628176
• Heavy Atom Count: 105
• Complexity: 2010

Purity/Quality:

99.5% ^*data from raw suppliers

2-Hydroxypropyl-β-cyclodextrin ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: UVCB,Other Classes -> Other Organic Compounds
• Canonical SMILES: CC(COCC1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)O)O)O
• Recent EU Clinical Trials: A Randomized, Placebo-controlled, Double-blind, Parallel group, 6 Month Study to Evaluate the Safety, Tolerability, and Potential Efficacy of Monthly Trappsol? Cyclo? (hydroxypropyl beta cyclodextrin, HPβCD) Infusions in Patients With Early Alzheimer’s Disease: A dose -range finding study
• Uses: 2-Hydroxypropyl-β-cyclodextrin (HBC) is a widely used modified cyclodextrin, the lipophilic cavity formed by 7 glucose units. Drug solubility in water is greatly enhanced by complexing with 2-Hydroxypropyl-β-cyclodextrin. enteric coating, sustained release formulations, buccal and transdermal drug delivery 2-Hydroxypropyl-β-cyclodextrin can be used as selective estrogen receptor modulator for the prevention of osteoporosis