C₂₇H₃₁FN₂O₆S

Base Information

• Chemical Name: C₂₇H₃₁FN₂O₆S
• CAS No.: 1415910-80-3
• Molecular Formula: C₂₇H₃₁FN₂O₆S
• Molecular Weight: 530.617
• Mol file: 1415910-80-3.mol

Synonyms:C₂₇H₃₁FN₂O₆S

Chemical Property of C₂₇H₃₁FN₂O₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₃₁FN₂O₆S

There total 6 articles about C₂₇H₃₁FN₂O₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-[1-(3-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrol-3-yl]glyoxylate → C27H31FN2O6S (1415910-80-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydroxylamine hydrochloride; sodium acetate / ethanol; 1,4-dioxane / 40 h / 90 °C

2: zinc; formic acid / ethanol / 0 - 20 °C

3: methanol / 18 h

With formic acid; hydroxylamine hydrochloride; sodium acetate; zinc; In 1,4-dioxane; methanol; ethanol;

DOI:10.1016/j.ejmech.2012.10.014

Reference yield:

2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro)phenyl]-1H-pyrrole → C27H31FN2O6S (1415910-80-3)

Guidance literature:

Multi-step reaction with 4 steps

1: titanium tetrachloride / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere

2: hydroxylamine hydrochloride; sodium acetate / ethanol; 1,4-dioxane / 40 h / 90 °C

3: zinc; formic acid / ethanol / 0 - 20 °C

4: methanol / 18 h

With formic acid; hydroxylamine hydrochloride; sodium acetate; titanium tetrachloride; zinc; In 1,4-dioxane; methanol; ethanol; dichloromethane;

DOI:10.1016/j.ejmech.2012.10.014

Reference yield:

1-[4-(methylthio)phenyl]pentane-1,4-dione (189501-33-5) → C27H31FN2O6S (1415910-80-3)

Guidance literature:

Multi-step reaction with 6 steps

1: potassium peroxymonosulfate / methanol; water / 2 h

2: toluene-4-sulfonic acid / ethanol / 0.75 h / 160 °C / 7757.43 Torr / Microwave irradiation

3: titanium tetrachloride / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere

4: hydroxylamine hydrochloride; sodium acetate / ethanol; 1,4-dioxane / 40 h / 90 °C

5: zinc; formic acid / ethanol / 0 - 20 °C

6: methanol / 18 h

With potassium peroxymonosulfate; formic acid; hydroxylamine hydrochloride; sodium acetate; titanium tetrachloride; toluene-4-sulfonic acid; zinc; In 1,4-dioxane; methanol; ethanol; dichloromethane; water;

DOI:10.1016/j.ejmech.2012.10.014

upstream raw materials:

1-[4-(methylthio)phenyl]pentane-1,4-dione

1-[4-(methylsulfonyl)phenyl]pentane-1,4-dione

4-(Methylthio)benzaldehyde

Downstream raw materials:

N-(tert-butoxycarbonyl)-2-[1-(3-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrol-3-yl]-2-amino-acetic acid

3-(nitrooxy)propyl N-(tert-butoxycarbonyl)-2-(1-(3-fluorophenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrol-3-yl)-2-amino-acetate

4-(nitrooxy)butyl N-(tert-butoxycarbonyl)-2-(1-(3-fluorophenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrol-3-yl)-2-amino-acetate

3-(nitrooxy)propyl-[2-amino-2-[1-(3-fluorophenyl)-2-methyl-5-(4-methylsulphonyl phenyl)-1H-pyrrol-3-yl]]-acetate