Technology Process of (-)-(S)-1-[2-(allyloxy)-6-methylhept-5-en-2-yl]-4-methylbenzene
There total 1 articles about (-)-(S)-1-[2-(allyloxy)-6-methylhept-5-en-2-yl]-4-methylbenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-allyloxymethyl-4-methylbenzene;
With
chromium(0) hexacarbonyl;
In
tetrahydrofuran; dibutyl ether;
for 44h;
Inert atmosphere;
Darkness;
Reflux;
With
n-butyllithium; (1S,2S)-1,2-diphenyl-N,N'-bis((R)-1-phenylethyl)ethane-1,2-diamine; lithium chloride;
In
tetrahydrofuran; hexanes;
at -78 ℃;
for 0.5h;
Inert atmosphere;
Darkness;
5-iodo-2-methylpent-2-ene; methyl iodide;
Further stages;
DOI:10.1002/ejoc.201000391
- Guidance literature:
-
(-)-(S)-1-[2-(allyloxy)-6-methylhept-5-en-2-yl]-4-methylbenzene;
With
tetrakis(triphenylphosphine) palladium(0);
In
methanol;
for 0.0833333h;
Inert atmosphere;
With
potassium carbonate;
In
methanol;
for 72h;
Inert atmosphere;
Reflux;
With
hydrogenchloride;
In
methanol; water;
at 20 ℃;
DOI:10.1002/ejoc.201000391
