C₆₆H₈₉N₃O₁₅Si

Base Information

Chemical Name:C₆₆H₈₉N₃O₁₅Si
CAS No.:262279-37-8
Molecular Formula:C₆₆H₈₉N₃O₁₅Si
Molecular Weight:1192.53
Hs Code.:

C<sub>66</sub>H<sub>89</sub>N<sub>3</sub>O<sub>15</sub>Si

Synonyms:C₆₆H₈₉N₃O₁₅Si

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Chemical Property of C₆₆H₈₉N₃O₁₅Si

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Technology Process of C₆₆H₈₉N₃O₁₅Si

There total 38 articles about C₆₆H₈₉N₃O₁₅Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 262279-42-5
9-{2''-[14-acetoxy-16-(5,5-dimethyl-[1,3]dioxan-2-yl)-6-hydroxy-4,8-dimethoxy-5,9,13,15-tetramethyl-12-oxo-hexadec-1-enyl]-[2,4';2',4'']teroxazol-4-yl}-3-(tert-butyl-diphenyl-silanyloxy)-9-methoxy-8-methyl-7-oxo-non-5-enoic acid

: 262279-37-8
C₆₆H₈₉N₃O₁₅Si

Guidance literature:: With dmap; 2,4,6-trichlorobenzoyl chloride; N-ethyl-N,N-diisopropylamine; In benzene; at 20 ℃;
DOI:10.1021/ja994003r

Reference yield:

: 194232-63-8
2''-(tert-Butyl-diphenyl-silanyloxymethyl)-[2,4';2',4'']teroxazole-4-carbaldehyde

: 262279-37-8
C₆₆H₈₉N₃O₁₅Si

Guidance literature:: Multi-step reaction with 12 steps

1.1: 65 percent / TiCl₄ / CH₂Cl₂ / 24 h / -78 - 20 °C

2.1: 93 percent / silver(I) oxide / 10 h / Heating

3.1: OsO₄; trimethylamine N-oxide dihydrate; t-BuOH / tetrahydrofuran; H₂O; toluene / 4 h / 20 °C

4.1: 773 mg / Pb(OAc)4; K₂CO₃ / diethyl ether / 0.25 h / 0 °C

5.1: 80 percent / NiCl₂; CrCl₂ / tetrahydrofuran; dimethylformamide / 20 °C

6.1: 99 percent / Dess-Martin periodinane; pyridine / CH₂Cl₂ / 0.5 h / 20 °C

7.1: 94 percent / TBAF / tetrahydrofuran / 0.08 h / 0 °C

8.1: 92 percent / CBr₄; PPh₃; 2,6-lutidine / dimethylformamide / 0.5 h

9.1: TFA / CH₂Cl₂ / 3 h / 0 °C

10.1: triethylphosphine / dimethylformamide / 0.5 h / 20 °C

10.2: 86 percent / DBU / dimethylformamide; tetrahydrofuran / 0.5 h / 0 °C

11.1: 65 percent / PPTS / ethanol / 22 h / 50 °C

12.1: 2,4,6-trichlorobenzoyl chloride; diisopropylethyl amine / benzene / 10 h / 20 °C

12.2: 66 percent / DMAP / benzene

With pyridine; 2,6-dimethylpyridine; chromium dichloride; lead(IV) acetate; osmium(VIII) oxide; carbon tetrabromide; trimethylamine-N-oxide; 2,4,6-trichlorobenzoyl chloride; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; titanium tetrachloride; potassium carbonate; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; triphenylphosphine; trifluoroacetic acid; nickel dichloride; silver(l) oxide; tert-butyl alcohol; triethylphosphine; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; benzene; 6.1: Dess-Martin oxidation / 10.1: Schlosser-Wittig olefination / 12.1: Yonemitsu/Yamaguchi reaction;
DOI:10.1021/ja002377a

Reference yield:

: 2,2-Dimethyl-propionic acid (3S,4R,5S)-5-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-4-methyl-7-oxo-heptyl ester

: 262279-37-8
C₆₆H₈₉N₃O₁₅Si

Guidance literature:: Multi-step reaction with 13 steps

1.1: 88 percent / TiCl₄ / CH₂Cl₂ / 8 h / -78 °C

2.1: 87 percent / Proton Sponge(R) / CH₂Cl₂ / 15 h / 0 - 25 °C

3.1: O₃; pyridine / methanol / 0.17 h / -78 °C

3.2: methylsulfide / methanol / 10 h / 25 °C

4.1: 1.18 g / CrCl₂ / tetrahydrofuran / 20 °C

5.1: 88 percent / NiCl₂; CrCl₂ / tetrahydrofuran; dimethylsulfoxide / 20 °C

6.1: NaNO₂; H₂ / PtO₂ / ethyl acetate; ethanol / 3 h / 3040.2 Torr

7.1: DIBAL-H / CH₂Cl₂; hexane / 2 h / -78 °C

8.1: 411 mg / Dess-Martin periodinane; pyridine / CH₂Cl₂ / 1.5 h / 20 °C

9.1: 87 percent / aq. DDQ / CH₂Cl₂ / 0.75 h / 20 °C

10.1: 82 percent / DMAP / CH₂Cl₂ / 0.5 h / 0 °C

11.1: triethylphosphine / dimethylformamide / 0.5 h / 20 °C

11.2: 86 percent / DBU / dimethylformamide; tetrahydrofuran / 0.5 h / 0 °C

12.1: 65 percent / PPTS / ethanol / 22 h / 50 °C

13.1: 2,4,6-trichlorobenzoyl chloride; diisopropylethyl amine / benzene / 10 h / 20 °C

13.2: 66 percent / DMAP / benzene

With pyridine; chromium dichloride; dmap; 2,4,6-trichlorobenzoyl chloride; hydrogen; pyridinium p-toluenesulfonate; titanium tetrachloride; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; diisobutylaluminium hydride; Dess-Martin periodane; ozone; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; nickel dichloride; sodium nitrite; triethylphosphine; platinum(IV) oxide; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide; benzene; 4.1: Takai olefination / 11.1: Schlosser-Wittig olefination / 13.1: Yonemitsu/Yamaguchi reaction;
DOI:10.1021/ja002377a