(1S)-N-<1-(ethoxycarbonyl)-3-oxo-3-phenylpropyl>-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride

Base Information

Chemical Name:(1S)-N-<1-(ethoxycarbonyl)-3-oxo-3-phenylpropyl>-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride
CAS No.:122442-04-0
Molecular Formula:C₂₄H₃₄N₂O₆*ClH
Molecular Weight:483.005
Hs Code.:

Synonyms:(1S)-N-<1-(ethoxycarbonyl)-3-oxo-3-phenylpropyl>-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S)-N-<1-(ethoxycarbonyl)-3-oxo-3-phenylpropyl>-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride

Chemical Property:

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Technology Process of (1S)-N-<1-(ethoxycarbonyl)-3-oxo-3-phenylpropyl>-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride

There total 1 articles about (1S)-N-<1-(ethoxycarbonyl)-3-oxo-3-phenylpropyl>-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 15121-89-8
ethyl (E)-4-oxo-4-phenyl-2-butenoate

: 29375-30-2
(S)-alanyl-(S)-proline tert-butyl ester

: 122442-04-0
(1S)-N-<1-(ethoxycarbonyl)-3-oxo-3-phenylpropyl>-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 0 ℃; for 2h;

Reference yield:

: 122442-04-0
(1S)-N-<1-(ethoxycarbonyl)-3-oxo-3-phenylpropyl>-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride

: 105499-26-1,105499-31-8,105560-98-3
(1S)-N-<1-(ethoxycarbonyl)-3-hydroxy-3-phenylpropyl>-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; Ambient temperature;

Reference yield:

: 122442-04-0
(1S)-N-<1-(ethoxycarbonyl)-3-oxo-3-phenylpropyl>-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride

: 105441-31-4
(3S,5R)-N-(tetrahydro-2-oxo-5-phenyl-3-furanyl)-(S)-alanyl-(S)-proline tert-butyl ester hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd on charcoal / ethanol / Ambient temperature

2: 25 percent / acetic acid / acetone / 24 h / Heating

With hydrogen; acetic acid; palladium on activated charcoal; In ethanol; acetone;