2-Chloro-3',4'-dihydroxyacetophenone

Base Information Edit

Chemical Name:2-Chloro-3',4'-dihydroxyacetophenone
CAS No.:99-40-1
Molecular Formula:C8H7ClO3
Molecular Weight:186.595
Hs Code.:29252900
European Community (EC) Number:202-754-8
NSC Number:17869,13905
UNII:FN6949L56Q
DSSTox Substance ID:DTXSID90243929
Nikkaji Number:J31.108A
Wikidata:Q27122818
Metabolomics Workbench ID:57922
ChEMBL ID:CHEMBL105609
Mol file:99-40-1.mol

Synonyms:99-40-1;2-Chloro-3',4'-dihydroxyacetophenone;2-Chloro-1-(3,4-dihydroxyphenyl)ethanone;4-(Chloroacetyl)catechol;3,4-Dihydroxyphenacyl chloride;Ethanone, 2-chloro-1-(3,4-dihydroxyphenyl)-;MFCD00002200;chloromethyl 3,4-dihydroxyphenyl ketone;UNII-FN6949L56Q;CHEMBL105609;.alpha.-Chloro-3',4'-dihydroxyacetophenone;CHEBI:51844;FN6949L56Q;EINECS 202-754-8;NSC-13905;NSC-17869;.alpha.-Chloro-3,4-dihydroxyacetophenone;Acetophenone, 2-chloro-3',4'-dihydroxy-;AI3-25258;3',4'-Dihydroxy-2-chloroacetophenone;NSC17869;3,4-Dihydroxy-alpha-chloroacetophenone;4-chloroacetylcatechol;4-chloroacetyl-catechol;Noradrenaline impurity E;4-Chloroacetylpyrocatechol;4-(chloroacetyl)-catechol;2-chloro-1-(3,4-dihydroxyphenyl)ethan-1-one;4-(Chloroacetyl)pyrocatechol;SCHEMBL43409;4-(2-chloroacetyl)pyrocatechol;DTXSID90243929;AMY21828;NSC13905;2-chlor-3',4'-dihydroxyacetophenon;2-chloro-3'4'-dihydroxyacetophenone;BBL011663;BDBM50119688;NSC 13905;NSC 17869;STK077070;2-chloro-3'4'-dihydroxy-acetophenone;2-Chloro3',4'-Ddihydroxyacetophenone;AKOS000120697;2-chloro-3',4'-dihydroxylacetophenone;4-(Chloroacetyl)-1,2-dihydroxybenzene;AC-7480;CS-W016884;2-chloro-3'',4''-dihydroxyacetophenone;NCGC00184201-01;NCGC00184201-02;alpha-Chloro-3',4'-dihydroxyacetophenone;AS-18630;SY049311;UPCMLD0ENAT0516-6643:001;1-CHLOROACETYL-3,4-DIHYDROXYBENZENE;FT-0611705;2-Chloro-1-(3,4-dihydroxyphenyl)ethanone #;2-Chloro-3',4'-dihydroxyacetophenone, 97%;EN300-17297;O10915;A846017;AT-051/43421153;W-100038;2-CHLORO-1-(3,4-DIHYDROXYPHENYL)-1-ETHANONE;ACETOPHENONE, .ALPHA.-CHLORO-3,4-DIHYDROXY-;NORADRENALINE TARTRATE IMPURITY E [EP IMPURITY];Q27122818;Z56912624;F0001-2334;Noradrenaline impurity E, European Pharmacopoeia (EP) Reference Standard

Suppliers and Price of 2-Chloro-3',4'-dihydroxyacetophenone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-1-(3,4-dihydroxyphenyl)ethanone
100g
$ 200.00

TRC
2-Chloro-1-(3,4-dihydroxyphenyl)ethanone
1g
$ 55.00

TCI Chemical
4-(Chloroacetyl)catechol >98.0%(HPLC)(T)
25g
$ 74.00

SynQuest Laboratories
3,4-Dihydroxyphenacyl chloride 97%
1 kg
$ 495.00

SynQuest Laboratories
3,4-Dihydroxyphenacyl chloride 97%
25 g
$ 20.00

SynQuest Laboratories
3,4-Dihydroxyphenacyl chloride 97%
100 g
$ 60.00

SynQuest Laboratories
3,4-Dihydroxyphenacyl chloride 97%
250 g
$ 135.00

Sigma-Aldrich
2-Chloro-3′,4′-dihydroxyacetophenone 97%
25g
$ 80.80

Sigma-Aldrich
Noradrenaline impurity E European Pharmacopoeia (EP) Reference Standard
y0000682
$ 190.00

Medical Isotopes, Inc.
2-Chloro-1-(3,4-dihydroxyphenyl)ethanone 97%
10 g
$ 320.00

Total 144 raw suppliers

Chemical Property of 2-Chloro-3',4'-dihydroxyacetophenone Edit

Chemical Property:

Melting Point:174-176 °C(lit.)
Boiling Point:418.7 °C at 760 mmHg
PKA:7.59±0.20(Predicted)
Flash Point:207 °C
PSA：57.53000
Density:1.444 g/cm³
LogP:1.51930
Storage Temp.:Refrigerator
Solubility.:Soluble in DMSO, methanol.
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:186.0083718
Heavy Atom Count:12
Complexity:172

Purity/Quality:

98% ^*data from raw suppliers

2-Chloro-1-(3,4-dihydroxyphenyl)ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(=O)CCl)O)O
Uses 2-Chloro-3',4'-dihydroxyacetophenone is used as a styptic adrenobazone, quasi adrenaline drug gasp spirit of intermediates.

Technology Process of 2-Chloro-3',4'-dihydroxyacetophenone

There total 19 articles about 2-Chloro-3',4'-dihydroxyacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%