2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-α-D-xylopyranosyle trichloroacetimidate

Base Information

• Chemical Name: 2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-α-D-xylopyranosyle trichloroacetimidate
• CAS No.: 1228797-71-4
• Molecular Formula: C₃₃H₂₄Cl₃N₅O₈
• Molecular Weight: 724.941
• Mol file: 1228797-71-4.mol

Synonyms:2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-α-D-xylopyranosyle trichloroacetimidate

Chemical Property of 2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-α-D-xylopyranosyle trichloroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-α-D-xylopyranosyle trichloroacetimidate

There total 1 articles about 2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-α-D-xylopyranosyle trichloroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-α/β-D-xylopyranose + trichloroacetonitrile (545-06-2) → 2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-α-D-xylopyranosyle trichloroacetimidate (1228797-71-4)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃; for 1.5h;

DOI:10.1016/j.ejmech.2011.05.076

Reference yield: 31.0%

3-O-pivaloyl-N-ethoxycarbonylnormorphine (1228578-48-0) + 2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-α-D-xylopyranosyle trichloroacetimidate (1228797-71-4) → 3-O-pivaloyl-N-ethoxycarbonylnormorphin-6-yl2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-β-D-xylopyranoside (1228797-72-5)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 1.5h;

DOI:10.1016/j.ejmech.2011.05.076

upstream raw materials:

trichloroacetonitrile

Downstream raw materials:

3-O-pivaloyl-N-ethoxycarbonylnormorphin-6-yl2,3,4-tri-O-benzoyl-5-C-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-β-D-xylopyranoside