Pyridine, 2-[1-(4-chlorophenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, (E)-

Base Information

• Chemical Name: Pyridine, 2-[1-(4-chlorophenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, (E)-
• CAS No.: 51657-94-4
• Molecular Formula: C₁₈H₁₉ClN₂
• Molecular Weight: 298.815
• DSSTox Substance ID: DTXSID501156180
• Mol file: 51657-94-4.mol

Synonyms:DTXSID501156180;Pyridine, 2-[1-(4-chlorophenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, (E)-;51657-94-4

Chemical Property of Pyridine, 2-[1-(4-chlorophenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, (E)-

Chemical Property:

• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 298.1236763
• Heavy Atom Count: 21
• Complexity: 341

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCN(C1)CC=C(C2=CC=C(C=C2)Cl)C3=CC=CC=N3
• Isomeric SMILES: C1CCN(C1)C/C=C(\C2=CC=C(C=C2)Cl)/C3=CC=CC=N3

Technology Process of Pyridine, 2-[1-(4-chlorophenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, (E)-

There total 2 articles about Pyridine, 2-[1-(4-chlorophenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1c-(4-chloro-phenyl)-1t-[2]pyridyl-3-pyrrolidino-propene (51657-94-4) + 1t-(4-chloro-phenyl)-1c-[2]pyridyl-3-pyrrolidino-propene (51714-99-9)

Guidance literature:

With sulfuric acid;

DOI:10.1039/jr9500001039 DOI:10.1038/168204a0

Reference yield:

sulfuric acid (7664-93-9) + 1t-(4-chloro-phenyl)-1c-[2]pyridyl-3-pyrrolidino-propene (51714-99-9) → 1c-(4-chloro-phenyl)-1t-[2]pyridyl-3-pyrrolidino-propene (51657-94-4)

Guidance literature:

Umwandlung in Abhaengigkeit von der Temperatur (80-200grad), Reaktionsdauer und Saeure-Konzentration;

Reference yield:

1c-(4-chloro-phenyl)-1t-[2]pyridyl-3-pyrrolidino-propene (51657-94-4) → 2-(4-chlorobenzoyl)pyridine (6318-51-0)

Guidance literature:

With chromium(VI) oxide; acetic acid;

upstream raw materials:

sulfuric acid

1t-(4-chloro-phenyl)-1c-[2]pyridyl-3-pyrrolidino-propene

Downstream raw materials:

1,1'-bis-(4-chloro-phenyl)-[3,3']biindolizinyl

2-(4-chlorobenzoyl)pyridine

3c-(4-chloro-phenyl)-3t-[2]pyridyl-allyl alcohol