N-(7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzamide

Base Information

Chemical Name:N-(7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzamide
CAS No.:18555-63-0
Molecular Formula:C₁₈H₁₈N₄O₅
Molecular Weight:370.365
Hs Code.:

Synonyms:N-(7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzamide

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of N-(7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzamide

There total 4 articles about N-(7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: C₂₇H₃₆N₄O₅Si

: 18555-63-0
N-(7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzamide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 27 ℃; for 12h;

Reference yield: 91.0%

: 18439-14-0
N⁴,N⁴,2',3',5'-O-Pentabenzoyltubercidin

: 18555-63-0
N-(7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzamide

Guidance literature:: With sodium methylate; In pyridine; methanol; for 0.333333h; Ambient temperature;

Reference yield:

: 69-33-0
tubercidin

: 98-88-4
benzoyl chloride

: 18555-63-0
N-(7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzamide

Guidance literature:: tubercidin; With pyridine; chloro-trimethyl-silane; at 0 ℃; for 1h;

benzoyl chloride; at 20 ℃; for 16h;

With ammonium hydroxide; In water; at 0 ℃;