Ethyl methyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)carbamate

Base Information

• Chemical Name: Ethyl methyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)carbamate
• CAS No.: 204704-95-0
• Molecular Formula: C20H22F3NO3
• Molecular Weight: 381.395
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID70472558
• Mol file: 204704-95-0.mol

Synonyms:204704-95-0;Ethyl methyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)carbamate;Ethyl N-methyl-N-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]carbamate;Ethyl methyl(3-phenyl-3-(4-(trifluoromethyl)-phenoxy)propyl)carbamate;Carbamic acid, N-methyl-N-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-, ethyl ester;Ethyl methyl{3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl}carbamate;C20H22F3NO3;ETHYL N-METHYL-N-{3-PHENYL-3-[4-(TRIFLUOROMETHYL)PHENOXY]PROPYL}CARBAMATE;SCHEMBL7939788;DTXSID70472558;AUXZZUAGZGDPRQ-UHFFFAOYSA-N;AKOS015963312;AC-8189;SB83736;CS-0216925;EN300-6482340;A814590;Z2301681690;Ethylmethyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)carbamate

Chemical Property of Ethyl methyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)carbamate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.513
• Boiling Point: 459.793 °C at 760 mmHg
• PKA: -1.38±0.70(Predicted)
• Flash Point: 231.875 °C
• PSA: 38.77000
• Density: 1.199g/cm³
• LogP: 5.30390
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 381.15517805
• Heavy Atom Count: 27
• Complexity: 444

Purity/Quality:

99% ^*data from raw suppliers

Ethyl methyl(3-phenyl-3-(4-(trifluoromethyl)-phenoxy)propyl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)N(C)CCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F

Technology Process of Ethyl methyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)carbamate

There total 1 articles about Ethyl methyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloroformic acid ethyl ester (541-41-3) + N,N-dimethyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)-1-propylamine (56225-81-1) → C20H22F3NO3 (204704-95-0)

Guidance literature:

With triethylamine; In toluene; at 80 ℃;

Reference yield:

C20H22F3NO3 (204704-95-0) → FLUOXETINE (54910-89-3,57226-07-0,100568-02-3,100568-03-4,59333-67-4)

Guidance literature:

C₂₀H₂₂F₃NO₃; With methylmagnesium chloride; In tetrahydrofuran; toluene; at 5 - 50 ℃;

With water; ammonium chloride; In tetrahydrofuran; toluene;

upstream raw materials:

chloroformic acid ethyl ester

N,N-dimethyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)-1-propylamine

Downstream raw materials:

FLUOXETINE

Refernces