Cyanoguanidine

Base Information Edit

Chemical Name:Cyanoguanidine
CAS No.:461-58-5
Deprecated CAS:125148-58-5,139351-77-2,139351-78-3,157480-33-6,166432-96-8,187414-06-8,205265-14-1,313058-80-9,1437797-89-1,1446334-90-2,1610803-20-7,200818-58-2,2377513-28-3,139351-77-2,139351-78-3,157480-33-6,166432-96-8,187414-06-8,205265-14-1
Molecular Formula:C₂H₄N₄
Molecular Weight:84.0806
Hs Code.:2926.20
European Community (EC) Number:207-312-8
ICSC Number:0650
NSC Number:2031
UNII:M9B1R0C16H
DSSTox Substance ID:DTXSID1020354
Nikkaji Number:J3.635H
Wikipedia:2-Cyanoguanidine
Wikidata:Q905401
ChEMBL ID:CHEMBL3183942
Mol file:461-58-5.mol

Synonyms:1-cyanoguanidine;cyanoguanidine;dicyandiamide;dicyandiamido;dicyandiamido sulfate

Suppliers and Price of Cyanoguanidine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Cyanoguanidine
100g
$ 323.00

Usbiological
Dermcidin
10ug
$ 350.00

TRC
CyanoguanidineMetforminRelatedCompoundAUSP
50g
$ 155.00

TCI Chemical
Dicyandiamide >98.0%(T)
25g
$ 15.00

TCI Chemical
Dicyandiamide >98.0%(T)
500g
$ 21.00

SynQuest Laboratories
Dicyandiamide
25 g
$ 25.00

Sigma-Aldrich
Cyanoguanidine (Metformin Related Compound A) Pharmaceutical Secondary Standard; Certified Reference Material
500mg
$ 68.10

Sigma-Aldrich
Dicyandiamide 99%
1kg
$ 51.10

Sigma-Aldrich
1-Cyanoguanidine for synthesis. CAS 461-58-5, chemical formula NCNHC(=NH)NH ., for synthesis
8024911000
$ 39.40

Sigma-Aldrich
1-Cyanoguanidine for synthesis
1 kg
$ 37.74

Total 271 raw suppliers

Chemical Property of Cyanoguanidine Edit

Chemical Property:

Appearance/Colour:white powder
Vapor Pressure:0.068mmHg at 25°C
Melting Point:208-211 °C(lit.)
Refractive Index:1.6260 (estimate)
Boiling Point:229.8 °C at 760 mmHg
PKA:0.73±0.70(Predicted)
Flash Point:92.8 °C
PSA：85.69000
Density:1.42 g/cm³
LogP:0.14148
Storage Temp.:2-8°C
Solubility.:H2O: 0.1 g/mL, clear
Water Solubility.:32 g/L (20 ºC)
XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:84.043596145
Heavy Atom Count:6
Complexity:100

Purity/Quality:

99% ^*data from raw suppliers

Cyanoguanidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn, T
Hazard Codes:Xn,T
Statements: 20/21/22-43-36/38-25
Safety Statements: 22-24/25-45-36-3

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Nitrogen Compounds -> Other Nitrogen Compounds
Canonical SMILES:C(#N)N=C(N)N
Chemical Composition and Structure Cyanoguanidine is a guanidine derivative in which one of the amino hydrogens of guanidine is substituted by a cyano group (-CN). It is composed of carbon, nitrogen, and hydrogen atoms.
Production Methods Cyanoguanidine can be produced synthetically by treating cyanamide with a base.
Cyanoguanidine can be produced industrially by reacting a metal oxide with a source of carbon to produce a finely divided metal carbide, which is then immediately reacted with nitrogen gas to form a metal cyanamide. This metal cyanamide can be further decomposed into cyanoguanidine and other compounds by reacting with water. Energy released from the reaction can be utilized, and metal hydroxide can be recovered for recycling.
Uses Manufacturing:
Cyanoguanidine is utilized in the manufacture of various products, including fertilizers, pharmaceuticals, explosives, oil well drilling muds, dyestuffs, and flame retardants.
Chemical Modification:
Cyanoguanidine is used for chemical modification of chitosan to improve its chemical stability and adsorption capacity for food dyes.
Metal Ion Binding:
Cyanoguanidine exhibits strong affinity for metal ions, particularly mercury (Hg(II)), making it useful for selective adsorption of heavy metals from aqueous solutions.
Ligand in Coordination Chemistry:
Cyanoguanidine acts as a ligand binding to metal ions via the nitrile nitrogen and the imine nitrogen, forming coordination complexes.
Impurity in Synthesis:
Cyanoguanidine can be an impurity in the synthesis of metformin, a medication for diabetes. Quantitation of cyanoguanidine in raw materials and pharmaceutical products is necessary for quality control and stability of metformin.

Technology Process of Cyanoguanidine

There total 53 articles about Cyanoguanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.7%