N₄-phenylmethyl-N₂-[2-[1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-1,2(R)-piperazinedicarboxamide

Base Information

• Chemical Name: N₄-phenylmethyl-N₂-[2-[1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-1,2(R)-piperazinedicarboxamide
• CAS No.: 281197-59-9
• Molecular Formula: C₃₁H₃₉ClN₆O₂
• Molecular Weight: 563.143

Synonyms:N₄-phenylmethyl-N₂-[2-[1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-1,2(R)-piperazinedicarboxamide

Chemical Property of N₄-phenylmethyl-N₂-[2-[1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-1,2(R)-piperazinedicarboxamide

Chemical Property:

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Technology Process of N₄-phenylmethyl-N₂-[2-[1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-1,2(R)-piperazinedicarboxamide

There total 2 articles about N₄-phenylmethyl-N₂-[2-[1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-1,2(R)-piperazinedicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N2-[2-[1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinecarboxamide (279238-48-1) + benzaldehyde (100-52-7) → N4-phenylmethyl-N2-[2-[1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinedicarboxamide (281197-59-9)

Guidance literature:

With sodium tris(acetoxy)borohydride; In dichloromethane; acetic acid; at 0 - 20 ℃; for 12h;

Reference yield:

→ N4-phenylmethyl-N2-[2-[1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinedicarboxamide (281197-59-9)

Guidance literature:

upstream raw materials:

N₂-[2-[1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-1,2(R)-piperazinecarboxamide

benzaldehyde

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