4-(2-Hydroxy-ethoxyMethyl)-piperidine-1-carboxylic acid benzyl ester

Base Information

Chemical Name:4-(2-Hydroxy-ethoxyMethyl)-piperidine-1-carboxylic acid benzyl ester
CAS No.:863615-19-4
Molecular Formula:C₁₆H₂₃NO₄
Molecular Weight:293.363
Hs Code.:
Mol file:863615-19-4.mol

Synonyms:benzyl 4-((2-hydroxyethoxy)methyl)piperidine-1-carboxylate

Suppliers and Price of 4-(2-Hydroxy-ethoxyMethyl)-piperidine-1-carboxylic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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A1 Biochem Labs
4-(2-Hydroxy-ethoxymethyl)-piperidine-1-carboxylicacidbenzylester 95%
1 g
$ 750.00

Total 1 raw suppliers

Chemical Property of 4-(2-Hydroxy-ethoxyMethyl)-piperidine-1-carboxylic acid benzyl ester

Chemical Property:

Boiling Point:446.2±25.0 °C(Predicted)
PKA:14.40±0.10(Predicted)
Density:1.155±0.06 g/cm3(Predicted)

Purity/Quality:: 4-(2-Hydroxy-ethoxymethyl)-piperidine-1-carboxylicacidbenzylester 95% ^*data from reagent suppliers

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Technology Process of 4-(2-Hydroxy-ethoxyMethyl)-piperidine-1-carboxylic acid benzyl ester

There total 3 articles about 4-(2-Hydroxy-ethoxyMethyl)-piperidine-1-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 167843-51-8
benzyl 4-((2-ethoxy-2-oxoethoxy)methyl)piperidine-1-carboxylate

: 863615-19-4
benzyl 4-((2-hydroxyethoxy)methyl)piperidine-1-carboxylate

Guidance literature:: With lithium borohydride; In tetrahydrofuran; at 25 ℃; for 12h;

Reference yield: 78.0%

: 863615-19-4
benzyl 4-((2-hydroxyethoxy)methyl)piperidine-1-carboxylate

Guidance literature:

Reference yield:

: 122860-33-7
benzyl 4-(hydroxymethyl)piperidine-N-carboxylate

: 863615-19-4
benzyl 4-((2-hydroxyethoxy)methyl)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: rhodium(II) acetate / dichloromethane / 0.5 h / 25 °C

1.2: 12 h / 25 °C

2.1: lithium borohydride / tetrahydrofuran / 12 h / 25 °C

With rhodium(II) acetate; lithium borohydride; In tetrahydrofuran; dichloromethane;