Technology Process of 4-(1-methoxyl-2-methylpropan-2-yl)benzene-1,2-diamine
There total 5 articles about 4-(1-methoxyl-2-methylpropan-2-yl)benzene-1,2-diamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
ethanol;
at 20 ℃;
for 12h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 3.5 h / 0 - 20 °C
1.2: 0.5 h / 20 °C / Cooling with ice
2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C / Inert atmosphere
2.2: 3 h / 20 °C
3.1: nitric acid / sulfuric acid / -20 °C
4.1: sodium azide / N,N-dimethyl-formamide / 20 °C
5.1: hydrogen / palladium 10% on activated carbon / ethanol / 20 °C / Inert atmosphere
With
lithium aluminium tetrahydride; sodium azide; hydrogen; nitric acid; sodium hydride;
sulfuric acid; palladium 10% on activated carbon;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; mineral oil;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C / Inert atmosphere
1.2: 3 h / 20 °C
2.1: nitric acid / sulfuric acid / -20 °C
3.1: sodium azide / N,N-dimethyl-formamide / 20 °C
4.1: hydrogen / palladium 10% on activated carbon / ethanol / 20 °C / Inert atmosphere
With
sodium azide; hydrogen; nitric acid; sodium hydride;
sulfuric acid; palladium 10% on activated carbon;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; mineral oil;
