N-((3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methyl)-2-(3-fluoro-4-(methylsulphonamido)phenyl)propanamide

Base Information

Chemical Name:N-((3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methyl)-2-(3-fluoro-4-(methylsulphonamido)phenyl)propanamide
CAS No.:1255040-29-9
Molecular Formula:C₁₉H₂₇FN₄O₃S
Molecular Weight:410.513
Hs Code.:

Synonyms:N-((3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methyl)-2-(3-fluoro-4-(methylsulphonamido)phenyl)propanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-((3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methyl)-2-(3-fluoro-4-(methylsulphonamido)phenyl)propanamide

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Technology Process of N-((3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methyl)-2-(3-fluoro-4-(methylsulphonamido)phenyl)propanamide

There total 8 articles about N-((3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methyl)-2-(3-fluoro-4-(methylsulphonamido)phenyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1243817-09-5
(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methanamine

: C₁₀H₁₁ClFNO₃S

: 1255040-29-9
N-((3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methyl)-2-(3-fluoro-4-(methylsulphonamido)phenyl)propanamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 20h;

Reference yield:

: 1243817-09-5
(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methanamine

: C₁₆H₁₆FNO₄S

: 1255040-29-9
N-((3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methyl)-2-(3-fluoro-4-(methylsulphonamido)phenyl)propanamide

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield:

: 824426-35-9
2-[3-fluoro-4-(methylsulfonylamino)phenyl]propionic acid

: 1243817-09-5
(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methanamine

: 1255040-29-9
N-((3-tert-butyl-1-methyl-1H-pyrazol-5-yl)methyl)-2-(3-fluoro-4-(methylsulphonamido)phenyl)propanamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 20h; Product distribution / selectivity;