4-Hydroxy-2-adamantone

Base Information

• Chemical Name: 4-Hydroxy-2-adamantone
• CAS No.: 26278-43-3
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Hs Code.: 2914400090
• Mol file: 26278-43-3.mol

Synonyms:Tricyclo[3.3.1.13,7]decanone, 4-hydroxy- (9CI);4-Hydroxy-2-adamantanone;Adamantan-4-ol-2-one;2-Adamantanone,4-hydroxy- (8CI);

Chemical Property of 4-Hydroxy-2-adamantone

Chemical Property:

• Boiling Point: 306.579 °C at 760 mmHg
• Flash Point: 129.58 °C
• PSA: 37.30000
• Density: 1.25 g/cm³
• LogP: 0.98240

Purity/Quality:

99% ^*data from raw suppliers

4-Hydroxyadamantan-2-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Hydroxy-2-adamantone

There total 7 articles about 4-Hydroxy-2-adamantone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

4(a)-(trifluoromethylsulfonyloxy)adamantan-2-one (134329-63-8,144490-91-5) → bicyclo<3.3.1>non-6-ene-3-endo-carboxylic acid (56820-19-0) + 4(a)-hydroxyadamantan-2-one (26278-43-3,27863-77-0,27863-78-1,51020-64-5,51020-65-6,103419-82-5,103419-83-6) + 4(e)-hydroxyadamantan-2-one (26278-43-3,27863-77-0,27863-78-1,51020-64-5,51020-65-6,103419-82-5,103419-83-6)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; water; acetone; for 1.5h; Heating;

Reference yield: 5.0%

4(a)-(trifluoromethylsulfonyloxy)adamantan-2-one (134329-63-8,144490-91-5) → bicyclo<3.3.1>non-6-ene-3-endo-carboxylic acid (56820-19-0) + 4(a)-hydroxyadamantan-2-one (26278-43-3,27863-77-0,27863-78-1,51020-64-5,51020-65-6,103419-82-5,103419-83-6) + 4(e)-hydroxyadamantan-2-one (26278-43-3,27863-77-0,27863-78-1,51020-64-5,51020-65-6,103419-82-5,103419-83-6)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; water; acetone; for 1.5h; Heating;

Reference yield:

4-oxohomoadamantan-5-one (21898-84-0) → 4e-Hydroxytricyclo<3.3.1.13,7>decan-2-on (26278-43-3,27863-77-0,27863-78-1,51020-64-5,51020-65-6,103419-82-5,103419-83-6) + 4a-Hydroxytricyclo<3.3.1.13,7>decan-2-on (26278-43-3,27863-77-0,27863-78-1,51020-64-5,51020-65-6,103419-82-5,103419-83-6)

Guidance literature:

With sulfuric acid; at 92 - 94 ℃; for 4.5h;

DOI:10.1002/hlca.19850680326

upstream raw materials:

4-oxohomoadamantan-5-one

4(a)-(trifluoromethylsulfonyloxy)adamantan-2-one

Downstream raw materials:

adamantane-2e, 4e-diol

adamantan-2e, 4a-diol

4-tert-butyl-2,11,11-trimethyl-15-oxa-2,4-ethanoadamantane

4a-tetrahydropyranoxy-2e-toluene-p-sulphonoxyadamantane