2-Fluoro-3-methylaniline

Base Information

• Chemical Name: 2-Fluoro-3-methylaniline
• CAS No.: 1978-33-2
• Molecular Formula: C7H8FN
• Molecular Weight: 125.146
• Hs Code.: 2921430090
• Mol file: 1978-33-2.mol

Synonyms:m-Toluidine,2-fluoro- (6CI,8CI);

Chemical Property of 2-Fluoro-3-methylaniline

Chemical Property:

• Vapor Pressure: 0.625mmHg at 25°C
• Refractive Index: 1.542
• Boiling Point: 187.613 °C at 760 mmHg
• PKA: 3.33±0.10(Predicted)
• Flash Point: 80.338 °C
• PSA: 26.02000
• Density: 1.115 g/cm³
• LogP: 2.29750
• Storage Temp.: 0-10°C

Purity/Quality:

99% ^*data from raw suppliers

2-Fluoro-3-methylaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,T,Xn
• Hazard Codes: Xi,T,Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Fluoro-3-methylaniline

There total 1 articles about 2-Fluoro-3-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-fluoro-3-nitrotoluene (437-86-5) → 2-fluoro-3-methyl-aniline (1978-33-2)

Guidance literature:

With hydrazine hydrate; In ethanol; at 75 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.catcom.2022.106398

Reference yield: 95.0%

2-fluoro-3-methyl-aniline (1978-33-2) + acryloyl chloride (814-68-6,25189-84-8) → C10H10FNO

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1002/cjoc.202100313

Reference yield: 89.0%

2-fluoro-3-methyl-aniline (1978-33-2) → 4-bromo-2-fluoro-3-methylaniline (1540204-53-2)

Guidance literature:

With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 20 ℃; for 1.5h;

DOI:10.1039/c9ob01718f

upstream raw materials:

2-fluoro-3-nitrotoluene

Downstream raw materials:

2-fluoro-3-methylacetanilide

N-(1-chloro-vinyl)-N,N'-bis-(2-fluoro-3-methyl-phenyl)-acetamidine

N-(2-fluoro-3-methylphenyl)-3,3-dimethoxypropanamide

(2-fluoro-3-methylphenyl)hydrazine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1978-33-2 2-Fluoro-3-methylaniline

Send

Send

Metric Ton KG G Pound L ML

Send

Send