2-Bromo-5-fluorobenzaldehyde

Base Information

Chemical Name:2-Bromo-5-fluorobenzaldehyde
CAS No.:94569-84-3
Molecular Formula:C7H4BrFO
Molecular Weight:203.011
Hs Code.:29130000
DSSTox Substance ID:DTXSID40378371
Nikkaji Number:J2.002.877G
Wikidata:Q72455735
Mol file:94569-84-3.mol

Synonyms:2-bromo-5-fluorobenzaldehyde

Suppliers and Price of 2-Bromo-5-fluorobenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromo-5-fluorobenzaldehyde
2.5 g
$ 55.00

TCI Chemical
2-Bromo-5-fluorobenzaldehyde >95.0%(GC)
25g
$ 148.00

TCI Chemical
2-Bromo-5-fluorobenzaldehyde >95.0%(GC)
5g
$ 50.00

SynQuest Laboratories
2-Bromo-5-fluorobenzaldehyde 98%
5 g
$ 18.00

SynQuest Laboratories
2-Bromo-5-fluorobenzaldehyde 98%
25 g
$ 44.00

Sigma-Aldrich
2-Bromo-5-fluorobenzaldehyde 96%
5g
$ 74.50

Sigma-Aldrich
2-Bromo-5-fluorobenzaldehyde 96%
1g
$ 21.00

Matrix Scientific
2-Bromo-5-fluorobenzaldehyde 95+%
100g
$ 98.00

Matrix Scientific
2-Bromo-5-fluorobenzaldehyde 95+%
25g
$ 37.00

Frontier Specialty Chemicals
2-Bromo-5-fluorobenzaldehyde 98%
25g
$ 268.00

Total 123 raw suppliers

Chemical Property of 2-Bromo-5-fluorobenzaldehyde

Chemical Property:

Vapor Pressure:0.0845mmHg at 25°C
Melting Point:51-56 °C(lit.)
Refractive Index:1.584
Boiling Point:225.8 °C at 760 mmHg
Flash Point:90.4 °C
PSA：17.07000
Density:1.67 g/cm³
LogP:2.40070
Storage Temp.:2-8°C
Sensitive.:Air Sensitive
Solubility.:Soluble in methanol.
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:201.94296
Heavy Atom Count:10
Complexity:129

Purity/Quality:

98% ^*data from raw suppliers

2-Bromo-5-fluorobenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)C=O)Br
Uses 2-Bromo-5-fluorobenzaldehyde is used as a precursor for the synthesis of 5-fluoro-3-substituted benzoxaboroles, which is used in material science as molecular receptors, building block in crystal engineering, as steroid conjugates for molecular imprinting , dyes and biosensors of alpha hydroxyl carboxylic acids. It is also used in the synthesis of 5-arylindazolo[3,2-b]quinazolin-7(5H)-one by reacting with 2-amino-N'-arylbenzohydrazide in the presence of Copper(I) bromide by the Ullmann-type reaction. 2-Bromo-5-fluorobenzaldehyde may be used in the synthesis of dihydrobenzoxaboroles bearing aryl, heteroaryl or vinyl substituents at the 1-position and 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole.

Technology Process of 2-Bromo-5-fluorobenzaldehyde

There total 13 articles about 2-Bromo-5-fluorobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 202865-66-5
2-bromo-5-fluorobenzyl alcohol

: 94569-84-3
2-bromo-5-fluorobenzaldehyde

Guidance literature:: With tert.-butylhydroperoxide; In toluene; at 120 ℃; for 4h;
DOI:10.1039/c7nj02062g

Reference yield: 87.0%

: C₈H₇BrFNO

: 94569-84-3
2-bromo-5-fluorobenzaldehyde

Guidance literature:: With formaldehyd; toluene-4-sulfonic acid; In tetrahydrofuran; water; at 100 ℃; for 0.25h; Microwave irradiation;
DOI:10.1021/jo200853j

Reference yield: 73.0%

: 452-63-1
2-Bromo-5-fluorotoluene

: 94569-84-3
2-bromo-5-fluorobenzaldehyde

Guidance literature:: With C₁₅H₁₁ClN₄SZn; p-benzoquinone; In tert-butyl alcohol; for 8h; Reagent/catalyst;
DOI:10.1016/j.jphotochem.2021.113455