C₁₁H₁₉NO₃

Base Information

• Chemical Name: C₁₁H₁₉NO₃
• CAS No.: 1601475-84-6
• Molecular Formula: C₁₁H₁₉NO₃
• Molecular Weight: 213.277
• Mol file: 1601475-84-6.mol

Synonyms:C₁₁H₁₉NO₃

Chemical Property of C₁₁H₁₉NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₁₉NO₃

There total 1 articles about C₁₁H₁₉NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S,3S,5S)-2-(tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-formic acid ethyl ester (214193-11-0) → C11H19NO3 (1601475-84-6)

Guidance literature:

Multi-step reaction with 6 steps

1: hydrogenchloride; water

2: N,N-dimethyl-formamide

3: lithium aluminium tetrahydride

4: trifluoroacetic anhydride; triethylamine

5: hydrogen; hydrogenchloride; palladium 10% on activated carbon / diethyl ether; water

6: sodium hydroxide / tetrahydrofuran

With hydrogenchloride; lithium aluminium tetrahydride; palladium 10% on activated carbon; water; hydrogen; triethylamine; trifluoroacetic anhydride; sodium hydroxide; In tetrahydrofuran; diethyl ether; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2014.02.055

Reference yield:

C11H19NO3 (1601475-84-6) → C27H32F3N3O4

Guidance literature:

Multi-step reaction with 4 steps

1: Dess-Martin periodane

2: 0 - 40 °C

3: HATU; N-ethyl-N,N-diisopropylamine

4: hydrogenchloride; water / 1,4-dioxane

With hydrogenchloride; water; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; HATU; In 1,4-dioxane; 2: |Bargellini Reaction;

DOI:10.1016/j.bmcl.2014.02.055

Reference yield:

C11H19NO3 (1601475-84-6) → C32H30F6N4O4 (1601475-81-3)

Guidance literature:

Multi-step reaction with 5 steps

1: Dess-Martin periodane

2: 0 - 40 °C

3: HATU; N-ethyl-N,N-diisopropylamine

4: hydrogenchloride; water / 1,4-dioxane

5: HATU

With hydrogenchloride; water; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; HATU; In 1,4-dioxane; 2: |Bargellini Reaction;

DOI:10.1016/j.bmcl.2014.02.055

upstream raw materials:

(1S,3S,5S)-2-(tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-formic acid ethyl ester

Downstream raw materials:

C₃₇H₃₄F₆N₄O₄

C₃₂H₃₀F₆N₄O₄