Chemical Property of N-(2-Acetamido)iminodiacetic acid
Chemical Property:
- Appearance/Colour:white to almost white powder
- Vapor Pressure:2E-12mmHg at 25°C
- Melting Point:219 °C (dec.)(lit.)
- Refractive Index:1.5010 (estimate)
- Boiling Point:524.9 °C at 760 mmHg
- PKA:6.6(at 25℃)
- Flash Point:271.3 °C
- PSA:120.93000
- Density:1.522 g/cm3
- LogP:-1.35680
- Storage Temp.:Store at RT.
- Solubility.:1 M NaOH: 0.05 M at 20 °C, clear, colorles
- Water Solubility.:soluble
- XLogP3:-3.9
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:6
- Exact Mass:190.05897142
- Heavy Atom Count:13
- Complexity:211
- Purity/Quality:
-
99% *data from raw suppliers
ADA *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- Safety Statements:
24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Other Uses -> Chelating Agents
- Canonical SMILES:C(C(=O)N)N(CC(=O)O)CC(=O)O
- Recent ClinicalTrials:DUAC? Early Onset Efficacy Study in Japanese Subjects
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Description
ADA is a zwitterionic buffer used in biochemistry and molecular biology. It is one of the Good buffers developed in the 1960′s to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The pioneering publication by Good and co-workers describes the synthesis of ADA and its physical properties. The useful range of ADA buffer in aqueous solution is 6.0 - 7.2.
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Uses
Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4).Used to prepare immobilized pH gradients. N-(2-Acetamido)iminodiacetic acid is buffer for biological systems and chelator for metals. ADA, or N-(2-Acetamido)iminodiacetic acid, can be used to study biological buffers and zwitterionic compounds. ADA has been used in a study to describe the application of scanning capacitively coupled contactless conductivity detection (SC(4)D) for the determination of pH dependant behaviour of two aminopolycarboxylates immobilised onto the surface of a monolithic capillary column.