Mometasone

Base Information

• Chemical Name: Mometasone
• CAS No.: 105102-22-5
• Molecular Formula: C22H28Cl2O4
• Molecular Weight: 521.44
• European Community (EC) Number: 818-819-4
• UNII: 8HR4QJ6DW8
• DSSTox Substance ID: DTXSID10872412
• Nikkaji Number: J536.076E
• Wikipedia: Mometasone_(prodrug),Mometasone
• Wikidata: Q28208887
• NCI Thesaurus Code: C66181
• RXCUI: 108118
• Metabolomics Workbench ID: 43061
• ChEMBL ID: CHEMBL1201404
• Mol file: 105102-22-5.mol

Synonyms:Asmanex;Asmanex Twisthaler;Elocon;Furoate Monohydrate, Mometasone;Furoate, Mometasone;mometasone;mometasone furoate;mometasone furoate monohydrate;Monohydrate, Mometasone Furoate;Nasonex;Rinelon;Sch 32088;Sch-32088;Sch32088;Twisthaler, Asmanex

Chemical Property of Mometasone

Chemical Property:

• Appearance/Colour: white to off-white crystalline powder
• Vapor Pressure: 4.47E-18mmHg at 25°C
• Melting Point: 220oC (decomposes)
• Refractive Index: 1.603
• Boiling Point: 586.6 °C at 760 mmHg
• PKA: 12.08±0.70(Predicted)
• Flash Point: 308.5 °C
• PSA: 93.81000
• Density: 1.35 g/cm³
• LogP: 4.86920
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 426.1364648
• Heavy Atom Count: 28
• Complexity: 806

Purity/Quality:

99% ^*data from raw suppliers

Mometasone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)Cl)C
• Isomeric SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CCl)O)C)O)Cl)C
• Recent ClinicalTrials: Prospective, Randomized, Multinational, Multicenter, Double-blind, Placebo and Active Controlled Trial in 4 Parallel-groups of Patients Suffering From Seasonal Allergic Rhinitis
• Recent EU Clinical Trials: A multicenter, randomized, double-blind, placebo and active controlled parallel-group trial to assess the efficacy and safety of the fixed combination medicinal product Mometasone furoate + Azelastine hydrochloride nasal spray (50 + 140 mcg) in the treatment of seasonal allergic rhinitis
• Recent NIPH Clinical Trials: A Randomized Placebo-controlled Trial of an Early Interventional Treatment with Mometasone Furoate Nasal Spray in Japanese Cedar/Cypress Pollinosis
• Uses: Mometasone is a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders. Mometasone (Mometasone EP Impurity G) is a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders.